https://scholars.lib.ntu.edu.tw/handle/123456789/473732
標題: | Prevalence of current oral HPV infection among 100 betel nut chewers or cigarette smokers in Northern Taiwan | 作者: | CHENG-PING WANG TSENG-CHENG CHEN Chen H.-H. Hsu W.-L. YIH-LEONG CHANG |
公開日期: | 2019 | 出版社: | Elsevier B.V. | 卷: | 118 | 期: | 1P1 | 起(迄)頁: | 203-208 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background: The incidence of HPV positive oropharyngeal cancer is increasing in Taiwan. Given this, it is critical to understand the prevalence of oral HPV infection since this cancer is potentially preventable. A community-based study was conducted to evaluate the prevalence of oral HPV infection and sexual behavior changes. Methods: Between January and December 2016, 100 subjects between 20 and 70 years-old with current/ever betel nut chewing or current cigarette smoking visited the Department of Health, New Taipei City. Subjects with cancer history or known HIV/AIDS were excluded. Sexual behavior information was collected through a questionnaire. Oral rinse samples and oropharyngeal swabs were obtained for HPV genotyping using the EasyChip HPV genotyping array (King-Car, Taiwan). Results: 92 men and 8 women were recruited. The prevalence of oral HPV infection was 3%, present between 60 and 70 (11%) and between 30 and 40 years old (4%). The prevalence of the first sexual contact at younger than 20 years old were 71.4%, 53.6%, 15.4% and 44% in <40, 40–49, 50–59 and 60+ years old, respectively (p for trend = 0.0036). The prevalence of 3 or more lifetime sexual partners were 60.7%, 57.1%, 23.1% and 16.7%, respectively for <40, 40–49, 50–59 and 60+ years old (p for trend = 0.0005). Conclusion: The prevalence of oral HPV infection is 3%, in current/ever betel nut chewers or current cigarette smokers in Northern Taiwan. Younger generation have more lifetime sexual partners and younger first sexual contact. This could explain the rising incidence of HPV positive oropharyngeal cancer in Taiwan. ? 2018 |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045009439&doi=10.1016%2fj.jfma.2018.03.013&partnerID=40&md5=e4756d5517caf3bf546a2fb7dcf23ce7 https://scholars.lib.ntu.edu.tw/handle/123456789/473732 |
ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2018.03.013 | SDG/關鍵字: | adult; aged; alcoholism; areca nut; Article; cigarette smoking; cohort analysis; drinking behavior; female; fibrosis; genotype; human; infection risk; leukoplakia; major clinical study; male; mastication; middle aged; mouth disease; mouth infection; oral submucosal fibrosis; papillomavirus infection; risk assessment; sexual behavior; sexuality; Taiwan; age; Alphapapillomavirus; Areca; cigarette smoking; genetics; oropharynx tumor; papillomavirus infection; prevalence; risk factor; virology; young adult; Adult; Age Factors; Aged; Alphapapillomavirus; Areca; Cigarette Smoking; Diagnosis, Oral; Female; Humans; Male; Middle Aged; Oropharyngeal Neoplasms; Papillomavirus Infections; Prevalence; Risk Factors; Sampling Studies; Taiwan; Young Adult |
顯示於: | 病理學科所 |
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