Quantitative analysis on optical properties of human atherosclerosis by using polarization-sensitive optical coherence tomography
Journal
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Journal Volume
6842
ISBN
9780819470171
Date Issued
2008
Author(s)
Abstract
In this research, we have used an algorithm to extract four different optical parameters, including the scattering coefficient (μs), effective anisotropy factor (goff), birefringence coefficient (Δn), and fast-axis angle (β) from polarization-sensitive optical coherence tomography (PS-OCT) images. The proposed method was evaluated from a set of phantoms and it yielded valid results. We demonstrate that the optical characteristic of normal and different kinds of atherosclerotic lesions in human vessel can be quantitatively described. Whether change in these quantified optical properties could be used to discriminate between different types of human atherosclerotic plaques was examined.
SDGs
Type
conference paper