Risk factors for nosocomial infective endocarditis in patients with methicillin-resistant Staphylococcus aureus bacteremia
Journal
Infection Control and Hospital Epidemiology
Journal Volume
26
Journal Issue
7
Pages
654-657
Date Issued
2005
Author(s)
Abstract
BACKGROUND AND OBJECTIVE: Nosocomial infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are increasing. Only a few studies of MRSA infective endocarditis have been conducted, and none have reported its risk factors. We sought to determine the host-related risk factors for infective endocarditis in patients with nosocomial MRSA bacteremia. SETTING: A 2,000-bed, university-affiliated, tertiary-care hospital. PATIENTS: Thirty-one patients with nosocomial MRSA infective endocarditis between October 1996 and May 2003. DESIGN: A retrospective chart review was conducted. Data were compared with those from a control group of patients with nosocomial MRSA bacteremia. Logistic regression was used to identify independent risk factors for nosocomial infective endocarditis. RESULTS: Compared with patients who had nosocomial MRSA bacteremia and no infective endocarditis, patients who had infective endocarditis had a higher incidence of chronic liver disease and a lower incidence of immunodeficiency. The risk of developing infective endocarditis was approximately 10% for patients with nosocomial MRSA bacteremia. CONCLUSION: Patients with MRSA bacteremia and underlying chronic liver disease were prone to infective endocarditis.
SDGs
Other Subjects
antibiotic agent; meticillin; adolescent; adult; aged; bacteremia; bacterial endocarditis; child; chronic liver disease; clinical article; controlled study; female; hospital infection; human; immune deficiency; incidence; male; methicillin resistant Staphylococcus aureus; retrospective study; review; risk factor; Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Case-Control Studies; Child; Child, Preschool; Comorbidity; Cross Infection; Endocarditis, Bacterial; Female; Humans; Infant; Infant, Newborn; Logistic Models; Male; Methicillin Resistance; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Factors; Staphylococcal Infections; Staphylococcus aureus; Taiwan
Type
review