Application of extracorporeal membrane oxygenation in adult burn patients
Journal
Artificial Organs
Journal Volume
25
Journal Issue
8
Pages
622-626
Date Issued
2001
Author(s)
Ko W.-J.
Jan G.-J.
Lin F.-Y.
Chu S.-H.
Abstract
Adult respiratory distress syndrome (ARDS) has been the major cause of mortality in bum injury. The authors reported the experience of using extracorporeal membrane oxygenation (ECMO) to treat adult burn patient with ARDS. Three patients with burn or electric injury, around 48.9% of body surface area over second-degree burns, developed ARDS after resuscitation. All had positive blood culture and depended on a ventilator more than 5 days before ECMO. Venovenous (VV) ECMO was started at the beginning of severe respiratory failure with an oxygen index of 61.6 ± 15.5 cm H2O/mm Hg (?40 cm H2O/mm Hg), partial arterial oxygen tension to inspired oxygen fraction (Pao2/Fio2) of 46.1 ± 7.0 mm Hg (?200 mm Hg), positive end expiratory pressure (PEEP) of 15.7 ± 1.6 cm H2O (?10 cm H2O), alveolar-arterial difference in oxygen concentration (A-a Do2) of 618.9 ± 19.3 mm Hg (?300 mm Hg), and lung compliance of 17.3 ± 4.6 ml/cm H2O (?30 ml/cm H2O). The VV type had to be converted to the newly designed veno-venoarterial (V-VA) ECMO due to the myocardial dysfunction. Two of three patients survived. The duration of ECMO was 160.2 ± 51.1 h. Two patients received debridement of escar during ECMO support and desmopressin infusion, and no increased bleeding or coagulopathy was found. The respiratory parameters were significantly improved after ECMO, especially in the survivors. ECMO is also suitable for ARDS in adult burn injury.
SDGs
Other Subjects
Oxygen; Oxygenation; Resuscitation; Acute respiratory distress syndrome; Blood culture; Body surface; Burn; Extracorporeal membrane oxygenation; Oxygen index; Respiratory distress syndrome; Respiratory failure; Surface area; Venovenous extracorporeal membrane oxygenation; Respiratory therapy; desmopressin; adult; adult respiratory distress syndrome; article; bleeding; blood clotting disorder; blood culture; burn; case report; cause of death; debridement; disease severity; electric burn; extracorporeal oxygenation; female; human; injury scale; lung alveolus oxygen tension; lung compliance; male; myocardial disease; positive end expiratory pressure; priority journal; respiratory failure; resuscitation; survival; treatment outcome; ventilator
Type
journal article