https://scholars.lib.ntu.edu.tw/handle/123456789/477842
標題: | Primary leiomyosarcoma of the nipple-areola complex: Report of a case and review of literature | 作者: | Luh S.-P. Wong L.-C. Huang P.-C. CHIUN-SHENG HUANG |
公開日期: | 2008 | 卷: | 9 | 期: | 2 | 起(迄)頁: | 109-113 | 來源出版物: | Journal of Zhejiang University: Science B | 摘要: | Primary leiomyosarcoma of the nipple-areola complex is extremely rare. Less than ten such cases have been reported in English literature so far. Herein we describe a 52-year-old female presenting with a 1.5 cm×1.1 cm×0.7 cm nodular lesion over her left nipple, and leiomyosarcoma was proved by pathological examination of the excised specimen. Positron emitted tomogram (PET) revealed no abnormal signal other than the primary site. Microscopically, this poorly circumscribed tumor was composed of interlacing bundles of smooth muscle cells with bizarre and pleomorphic nuclei, as well as prominent nucleoli. Its mitotic count was up to 7 mitoses per 10 high power fields (HPF). Immunohistochemical study of tumor cells revealed positive stain for α-smooth muscle actin and vimentin; and negative for cytokeratin, CD34 and S-100. Left simple mastectomy was undertaken and no residual mass lesion was noted on the resected specimen. Related literatures about the diagnosis and treatment for breast leiomyosarcoma will be presented here. ? Springer-Verlag 2008. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-39049122070&doi=10.1631%2fjzus.B0720246&partnerID=40&md5=a37b8c9cc6b7a268b57751ea843c0b9f https://scholars.lib.ntu.edu.tw/handle/123456789/477842 |
ISSN: | 1673-1581 | DOI: | 10.1631/jzus.B0720246 | SDG/關鍵字: | CD34 antigen; cytokeratin; protein S 100; smooth muscle actin; vimentin; adult; article; breast areola; breast cancer; case report; female; histopathology; human; human tissue; immunohistochemistry; leiomyosarcoma; mastectomy; medical literature; microscopy; nipple; positron emission tomography; priority journal; treatment response; Antigens, CD34; Breast; Breast Neoplasms; Cell Nucleus; Female; Humans; Immunohistochemistry; Leiomyosarcoma; Mastectomy; Middle Aged; Myocytes, Smooth Muscle; Nipples; S100 Proteins; Smooth Muscle Tumor; Treatment Outcome |
顯示於: | 醫學系 |
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