Behavioral-educational sleep interventions for pediatric epilepsy: A randomized controlled trial
Journal
Sleep
Journal Volume
43
Journal Issue
1
Pages
zsz211
Date Issued
2020
Abstract
Study Objectives: To evaluate the effect of a clinic-based, behavioral-educational sleep intervention on sleep of children with epilepsy, maternal knowledge about childhood sleep, and maternal sleep quality. Methods: A total of 100 toddlers and preschool-age children with epilepsy (1.5-6 years, 55% boys) and their parents were randomized to receive sleep intervention (n = 50) or usual care with attention (n = 50). Outcomes were assessed at baseline, 3, 6, and 12 months after intervention with the use of objective actigraphy, Children's Sleep Habits Questionnaire, Parents' Sleep Knowledge Inventory, and Pittsburgh Sleep Quality Index. Intervention effects were examined using general linear models for repeated measurements to compare the mean change in outcomes from baseline to 12 months post-intervention between the two groups. Results: Sleep intervention resulted in children having greater sleep efficiency by 2.03% compared with the usual care group (95% CI = 0.20% to 3.86%; p =. 03). Children in the intervention group also had significantly longer total nighttime sleep as objectively assessed by actigraphy than did those in the usual care group, with an adjusted mean difference of 16.13 minutes (95% CI = 0.24% to 32.03%; p =. 04). No intervention effects were observed for maternal knowledge about childhood sleep, and maternal sleep quality. Conclusion: Sleep intervention provided during routine neurologic visits results in significant, measurable, and sustained benefits in sleep quality and quantity in children with epilepsy. Future trials are warranted to evaluate whether improvements in sleep could impact health-related quality of life or other aspects of functioning in children with epilepsy. Clinical Trial: This trial has been registered at www.clinicaltrials.gov (trial name: Sleep Intervention for Pediatric Epilepsy; registration number: NCT02514291). ? 2019 Sleep Research Society 2019. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.
SDGs
Other Subjects
anticonvulsive agent; actimetry; Article; child; child behavior; Childrens Sleep Habits Questionnaire; clinical education; controlled study; epilepsy; female; follow up; human; major clinical study; male; Parents Sleep Knowledge Inventory; Pittsburgh Sleep Quality Index; preschool child; priority journal; questionnaire; randomized controlled trial; sleep; sleep parameters; sleep pattern; sleep quality; sleep time; attitude to health; child parent relation; education; epilepsy; health education; health promotion; infant; physiology; procedures; psychology; quality of life; sleep; Actigraphy; Child; Child, Preschool; Education, Nonprofessional; Epilepsy; Female; Health Education; Health Knowledge, Attitudes, Practice; Health Promotion; Humans; Infant; Male; Parents; Quality of Life; Sleep; Surveys and Questionnaires
Type
journal article