Acquisition of Mycobacterium abscessus among ventilator-dependent patients in Taiwan chronic respiratory care facilities
Journal
Future Microbiology
Journal Volume
11
Journal Issue
4
Pages
491-500
Date Issued
2016
Author(s)
Tsai C.-J.
Hu J.-Y.
Lee S.-W.
Abstract
AIM: To investigate the acquisition of Mycobacterium abscessus among ventilator-dependent patients. MATERIALS & METHODS: We prospectively recruited ventilator-dependent patients in five respiratory care wards (RCWs). Respiratory specimens were cultured for mycobacteria on day 1 (D1), 3 months (M3) and 6 months (M6) after enrollment. RESULTS: 72 patients had cultures taken at all three time points. The proportion of patients with a culture positive for M. abscessus increased from 15.3% (11/72) on D1 to 30.6% (22/72) at M3 and 38.9% (28/72) at M6. Two M. abscessus subspecies abscessus isolates obtained from different patients had identical randomly amplified polymorphic DNA patterns. Being in RCW D and advanced age were significantly associated with initial cultures positivity. CONCLUSION: Our study reveals that acquisition of M. abscessus was common among ventilator-dependent patients.
SDGs
Type
journal article