Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Medicine / 醫學院
  3. National Taiwan University Hospital / 醫學院附設醫院 (臺大醫院)
  4. Correlation between antimicrobial consumption and resistance among Staphylococcus aureus and enterococci causing healthcare-associated infections at a university hospital in Taiwan from 2000 to 2009
 
  • Details

Correlation between antimicrobial consumption and resistance among Staphylococcus aureus and enterococci causing healthcare-associated infections at a university hospital in Taiwan from 2000 to 2009

Journal
European Journal of Clinical Microbiology and Infectious Diseases
Journal Volume
30
Journal Issue
2
Pages
265-271
Date Issued
2011
Author(s)
Lai C.C.
Wang C.Y.
Chu C.C.
Tan C.K.
Lu C.L.
Lee Y.L.
YU-TSUNG HUANG  
PING-ING LEE  
PO-REN HSUEH  
DOI
10.1007/s10096-010-1081-1
URI
https://scholars.lib.ntu.edu.tw/handle/123456789/480061
Abstract
This study investigated the correlation between antibiotic consumption and resistance among Staphylococcus aureus and enterococci causing healthcare-associated infections at a university hospital in Taiwan from 2000 to 2009. Overall, the trend of total consumption (defined daily dose [DDD] per 1,000 patient-days) of glycopeptides, including vancomycin and teicoplanin, significantly increased during 2000 to 2003 and remained stable during 2004-2009. Vancomycin consumption significantly increased during 2003 and decreased after 2004. A significant decrease in the resistance rate with time was found for oxacillin- and gentamicin-resistant S. aureus. In contrast, the rates of vancomycin- and teicoplanin-resistant enterocci increased significantly. A significant correlation was found between the increased use of extended-spectrum cephalosporins, β-lactam-β-lactamase inhibitor combinations, carbapenems and the decreased prevalence of methicillin-resistant S. aureus (MRSA). In contrast, the increased use of teicoplanin, extended-spectrum cephalosporins, β-lactam-β-lactamase inhibitor combinations, and carbapenems was correlated with the increased prevalence of vancomycin-resistant enterococci (VRE). In conclusion, this 10-year study in a single institution identified different correlations between the prescription of antibiotics and the resistance rates of MRSA and VRE. Strict implementation of infection control policy based on these correlates would be helpful in decreasing the presence of these multidrug-resistant pathogens in hospitals. ? 2010 Springer-Verlag.
SDGs

[SDGs]SDG3

Other Subjects
amikacin; aminoglycoside antibiotic agent; beta lactam antibiotic; beta lactamase inhibitor; carbapenem derivative; cefepime; cefotaxime; cefpirome; ceftazidime; ceftriaxone; cephalosporin derivative; ciprofloxacin; ertapenem; fusidic acid; gentamicin; imipenem; levofloxacin; linezolid; meropenem; oxacillin; piperacillin plus tazobactam; polypeptide antibiotic agent; quinoline derived antiinfective agent; teicoplanin; timentin; vancomycin; antibiotic resistance; article; controlled study; drug use; Enterococcus; Enterococcus faecalis; hospital infection; human; major clinical study; methicillin resistant Staphylococcus aureus; prescription; priority journal; Staphylococcus aureus; Taiwan; trend study; university hospital; vancomycin resistant Enterococcus; Anti-Bacterial Agents; beta-Lactams; Cross Infection; Drug Resistance, Bacterial; Drug Utilization; Enterococcus; Glycopeptides; Gram-Positive Bacterial Infections; Humans; Staphylococcus aureus; Taiwan; Teicoplanin; Vancomycin
Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science