https://scholars.lib.ntu.edu.tw/handle/123456789/481538
標題: | Photodynamic therapeutic ablation for peripheral pulmonary malignancy via electromagnetic navigation bronchoscopy localization in a hybrid operating room (OR): A pioneering study | 作者: | KE-CHENG CHEN JANG-MING LEE |
關鍵字: | Electromagnetic navigation bronchoscopy (ENB); Peripheral-type lung malignancy; Photodynamic therapy (PDT); SuperDimension | 公開日期: | 2018 | 出版社: | AME Publishing Company | 卷: | 10 | 起(迄)頁: | S725-S730 | 來源出版物: | Journal of Thoracic Disease | 摘要: | Background: With the aid of electromagnetic navigation bronchoscopy (ENB), it has become possible to approach peripheral lung tumors from the airway. Meanwhile, local ablation using photodynamic therapy (PDT) has shown increasing promise in the realm of lung cancer treatment. The purpose of this study was to explore an alternative ablation method using PDT with SuperDimension ENB localization in a hybrid operating theater. Methods: Our study includes patients with primary or metastatic lung cancer who underwent PDT via ENB in the hybrid operating room (OR) of National Taiwan University Hospital between January 2016 and January 2017. ENB with the SuperDimension Navigation System (7th edition) was performed before PDT ablation to localize the target lesions. PDT ablation was performed with the assistance of intraoperative Dyna-computed tomography (Dyna-CT). Tumor response was evaluated by CT 3 months after the procedure. Results: Three patients underwent lung interstitial PDT via the aid of ENB during the study period. The mean size of the nodules was 21.3 mm. The mean navigation time was 14.3 minutes. In all cases, the target pulmonary nodule was ablated by PDT successfully. No major procedure-related complications occurred. One patient suffered from skin hypersensitivity one month after the procedure. The follow-up CT showed significant tumor shrinkage for all the patients. They were all discharged without incident a few days after the procedure as scheduled. Conclusions: PDT with SuperDimension ENB guidance in the hybrid OR is a novel and feasible approach to control peripheral lung malignancy. ? Journal of Thoracic Disease. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045221827&doi=10.21037%2fjtd.2018.03.139&partnerID=40&md5=ea604b4b544ec61007dd5fcd6e851f04 https://scholars.lib.ntu.edu.tw/handle/123456789/481538 |
ISSN: | 2072-1439 | DOI: | 10.21037/jtd.2018.03.139 | SDG/關鍵字: | adult; aged; Article; bronchoscopy; clinical article; computer assisted tomography; electromagnetic navigation bronchoscopy; electromagnetism; female; follow up; hospital discharge; human; lung cancer; lung nodule; male; middle aged; photodynamic therapy; postoperative complication; prospective study; skin allergy; tumor ablation; tumor volume |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。