Scaffolds and cell-based tissue engineering for blood vessel therapy
Journal
Cells Tissues Organs
Journal Volume
202
Journal Issue
5/6
Pages
281-295
Date Issued
2016
Author(s)
Hsia, K., Yao, C.-L., Chen, W.-M., Chen, J.-H., Lee, H., Lu, J.-H.
Abstract
The increasing morbidity of cardiovascular diseases in modern society has made it crucial to develop a small-caliber blood vessel. In the absence of appropriate autologous vascular grafts, an alternative prosthesis must be constructed for cardiovascular disease patients. The aim of this article is to describe the advances in making cell-seeded cardiovascular prostheses. It also discusses the combinations of types of scaffolds and cells, especially autologous stem cells, which are suitable for application in tissue-engineered vessels with the favorable properties of mechanical strength, antithrombogenicity, biocompliance, anti-inflammation, fatigue resistance and long-term durability. This article highlights the advancements in cellular tissue-engineered vessels in recent years. ? 2016 S. Karger AG, Basel.
Subjects
Blood vessels; Endothelial progenitor cell; Mesenchymal stem cell; Scaffold; Smooth muscle cell; Tissue engineering
SDGs
Other Subjects
adipose derived stem cell; blood vessel; blood vessel prosthesis; bone marrow derived mesenchymal stem cell; endothelial progenitor cell; human; mesenchymal stem cell; nonhuman; priority journal; Review; stem cell; tissue engineering; tissue scaffold; animal; blood vessel prosthesis; chemistry; cytology; drug effects; procedures; stem cell; tissue engineering; tissue scaffold; biomaterial; Animals; Biocompatible Materials; Blood Vessel Prosthesis; Humans; Stem Cells; Tissue Engineering; Tissue Scaffolds
Type
journal article