https://scholars.lib.ntu.edu.tw/handle/123456789/483174
標題: | Tai Chi Chuan training is associated with enhanced endothelium-dependent dilation in skin vasculature of healthy older men | 作者: | Wang J.-S. Lan C. SSU-YUAN CHEN Wong M.-K. |
公開日期: | 2002 | 卷: | 50 | 期: | 6 | 起(迄)頁: | 1024-1030 | 來源出版物: | Journal of the American Geriatrics Society | 摘要: | OBJECTIVES: The vascular endothelium modulates vascular tone by synthesizing and metabolizing vasoactive substances. Endothelium-dependent vasodilation declines with age. This study investigated whether Tai Chi Chuan (TCC) training could enhance endothelial function in the skin vasculature of older men. SETTING: Community setting. DESIGN: Basic hemodynamic characteristics and skin vascular response to endothelium-dependent and -independent vasodilators were studied. PARTICIPANTS: Ten older men who practiced TCC, 10 older healthy sedentary men, and 12 younger healthy sedentary men. The older TCC subjects had practiced classical Yang TCC for a mean ± standard deviation of 11.2 ± 3.4 years; mean attendance was 5.1 ± 1.8 times weekly. Sedentary subjects had not participated in any regular exercise training for at least 5 years. MEASUREMENTS: Different doses of 1% acetylcholine (ACh) and 1% sodium nitroprusside (SNP) were iontophoretically applied to the skin of subjects' lower legs, and cutaneous microvascular perfusion responses were determined by laser doppler measurements. Additionally, arterial and venous hemodynamic variables were measured by impedance plethysmograph. RESULTS: The older TCC group had higher lower leg arterial blood flow (LABF); LABF in response to reactive hyperemia; and lower leg venous capacity, tone and blood flow than their sedentary counterparts, but the older TCC group displayed similar arterial and venous hemodynamic variables to the younger sedentary group. The younger sedentary group had a higher ACh-induced cutaneous perfusion and a higher ratio of ACh- to SNP-induced cutaneous perfusion than the two older groups. The older TCC group showed a higher ACh-induced cutaneous perfusion and a higher ratio of ACh- to SNP-induced cutaneous perfusion than the older sedentary group. Skin vascular responses to SNP did not differ significantly between the three groups. CONCLUSIONS: Regular practice of TCC is associated with enhanced endothelium-dependent dilation in skin vasculature of older individuals. Moreover, TCC training may delay the age-related decline of venous compliance and hyperemic arterial response. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036084977&doi=10.1046%2fj.1532-5415.2002.50256.x&partnerID=40&md5=ec937c58755d8c22fec7b81f928e764d https://scholars.lib.ntu.edu.tw/handle/123456789/483174 |
ISSN: | 0002-8614 | DOI: | 10.1046/j.1532-5415.2002.50256.x | SDG/關鍵字: | acetylcholine; nitroprusside sodium; adult; age; aged; aging; artery blood flow; article; community; hemodynamics; human; human experiment; hyperemia; impedance plethysmography; iontophoresis; laser Doppler flowmetry; leg; male; microvasculature; normal human; sitting; skin blood flow; skin blood vessel; training; vascular endothelium; vasodilatation; vein compliance; Adult; Aged; Endothelium, Vascular; Exercise Test; Hemodynamic Processes; Humans; Laser-Doppler Flowmetry; Leg; Male; Plethysmography, Impedance; Regional Blood Flow; Skin; Tai Ji; Vasodilation |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。