https://scholars.lib.ntu.edu.tw/handle/123456789/483561
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | MING-YEN HSIAO | en_US |
dc.contributor.author | Hung C.-Y. | en_US |
dc.contributor.author | KE-VIN CHANG | en_US |
dc.contributor.author | DER-SHENG HAN | en_US |
dc.contributor.author | TYNG-GUEY WANG | en_US |
dc.creator | Hsiao M.-Y.;Hung C.-Y.;Chang K.-V.;Han D.-S.;Tyng-Guey Wang | - |
dc.date.accessioned | 2020-04-08T02:10:30Z | - |
dc.date.available | 2020-04-08T02:10:30Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1533-3159 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84942090923&partnerID=40&md5=c95c31d920d3eb557830823a30d95e1c | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/483561 | - |
dc.description.abstract | Background: Chronic widespread pain (CWP) is a global musculoskeletal disorder leading todisability and a reduced quality of life. Low levels of serum vitamin D has long been proposedto be associated with CWP, but previous research remains inconclusive.Objectives: To determine whether hypovitaminosis D was independently associated withCWP.Study Design: Meta-analysis of observational study.Methods: Electronic databases were searched for studies published up to November 2014comparing the prevalence of hypovitaminosis D and serum vitamin D levels between participantswith and without CWP. The crude and adjusted odds ratios (ORs) of hypovitaminosis D withCWP were calculated. Subgroup analysis according to gender, threshold of hypovitaminosis,and definition of patients was performed, as well as meta-regression to test the linearrelationship between crude ORs and the latitude of study locations.Results: Twelve studies were included, comprising 1,854 patients with CWP. The patientgroup showed a significantly higher risk of hypovitaminosis D than the control group (crudeOR, 1.63; 95% CI, 1.20 – 2.23). The association was slightly attenuated after adjustingconfounders, with a pooled adjusted OR of 1.41 (95% CI, 1.00 – 2.00). There was an increasein ORs of hypovitaminosis D using a lower diagnostic value of serum vitamin D (8 and 10ng/mL). The subgroup analysis according to gender and definition of CWP did not revealsignificant between-group differences. The meta-regression showed no linear relationshipbetween latitude and the crude ORs.Conclusions: There was a positive crude association between hypovitaminosis D and CWP,and the association was likely to remain after adjusting confounding factors. Use of a cut-offvalue of hypovitaminosis D (8 – 10 ng/mL) could better define the population with and withoutCWP. Further prospective follow-up studies are warranted to clarify the causal relationshipbetween hypovitaminosis D and CWP. ? 2015, American Society of Interventional Pain Physicians. All rights reserved. | en_US |
dc.publisher | American Society of Interventional Pain Physicians | en_US |
dc.relation.ispartof | Pain Physician | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | vitamin D; age; Article; chronic pain; data processing; disease association; fibromyalgia; gender; human; meta analysis; quality of life; vitamin blood level; vitamin D deficiency; blood; chronic pain; complication; fibromyalgia; observational study; prevalence; vitamin D deficiency; Chronic Pain; Fibromyalgia; Humans; Observational Studies as Topic; Prevalence; Vitamin D Deficiency | - |
dc.title | Is serum hypovitaminosis D associated with chronic widespread pain including fibromyalgia? A meta-analysis of observational studies | en_US |
dc.type | journal article | en |
dc.identifier.pmid | 26431141 | - |
dc.identifier.scopus | 2-s2.0-84942090923 | - |
dc.relation.pages | E877-E887 | en_US |
dc.relation.journalvolume | 18 | en_US |
dc.relation.journalissue | 5 | en_US |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Physical Medicine and Rehabilitation | - |
crisitem.author.dept | Physical Medicine and Rehabilitation-NTUH | - |
crisitem.author.dept | Physical Medicine and Rehabilitation | - |
crisitem.author.dept | Physical Medicine and Rehabilitation-NTUHBH | - |
crisitem.author.dept | Physical Medicine and Rehabilitation | - |
crisitem.author.dept | Physical Medicine and Rehabilitation-NTUHBH | - |
crisitem.author.dept | Physical Medicine and Rehabilitation | - |
crisitem.author.dept | Physical Medicine and Rehabilitation-NTUH | - |
crisitem.author.orcid | 0000-0001-9062-1027 | - |
crisitem.author.orcid | 0000-0002-6686-806X | - |
crisitem.author.orcid | 0000-0001-7642-8060 | - |
crisitem.author.orcid | 0000-0003-3298-4916 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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