|Title:||Early-onset Stroke in a Patient With Nasopharyngeal Cancer Associated With Protein C Deficiency||Authors:||Chiu Y.-N.
|Issue Date:||2009||Journal Volume:||108||Journal Issue:||7||Start page/Pages:||592-594||Source:||Journal of the Formosan Medical Association||Abstract:||
We report a 47-year-old male stroke patient with nasopharyngeal cancer (NPC) and protein C deficiency. The patient was diagnosed with NPC and received a complete course of radiotherapy. Infarction stroke occurred 28 months after radiotherapy and magnetic resonance imaging of the brain confirmed the diagnosis. Carotid duplex sonography showed 50-79% stenosis in his left internal carotid artery. Coagulation profiles indicated protein C deficiency. After medical treatment and rehabilitation, the patient regained the ability to walk and he could perform most of his daily activities. Radiotherapy-induced carotid stenosis is an exacerbating feature of stroke in patients with protein C deficiency. We suggest early carotid duplex sonography and survey of the coagulation profile to prevent a stroke in patients with NPC. ? 2009 Formosan Medical Association & Elsevier.
|ISSN:||0929-6646||DOI:||10.1016/S0929-6646(09)60378-8||SDG/Keyword:||adult; article; blood clotting; cancer patient; carotid artery obstruction; case report; daily life activity; disease exacerbation; echography; human; internal carotid artery; male; nasopharynx carcinoma; nuclear magnetic resonance imaging; protein C deficiency; stroke; stroke patient; walking; Carotid Stenosis; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Protein C Deficiency; Stroke; Ultrasonography, Doppler, Duplex
|Appears in Collections:||醫學系|
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