Early-onset Stroke in a Patient With Nasopharyngeal Cancer Associated With Protein C Deficiency
Journal
Journal of the Formosan Medical Association
Journal Volume
108
Journal Issue
7
Pages
592-594
Date Issued
2009
Author(s)
Abstract
We report a 47-year-old male stroke patient with nasopharyngeal cancer (NPC) and protein C deficiency. The patient was diagnosed with NPC and received a complete course of radiotherapy. Infarction stroke occurred 28 months after radiotherapy and magnetic resonance imaging of the brain confirmed the diagnosis. Carotid duplex sonography showed 50-79% stenosis in his left internal carotid artery. Coagulation profiles indicated protein C deficiency. After medical treatment and rehabilitation, the patient regained the ability to walk and he could perform most of his daily activities. Radiotherapy-induced carotid stenosis is an exacerbating feature of stroke in patients with protein C deficiency. We suggest early carotid duplex sonography and survey of the coagulation profile to prevent a stroke in patients with NPC. ? 2009 Formosan Medical Association & Elsevier.
SDGs
Other Subjects
adult; article; blood clotting; cancer patient; carotid artery obstruction; case report; daily life activity; disease exacerbation; echography; human; internal carotid artery; male; nasopharynx carcinoma; nuclear magnetic resonance imaging; protein C deficiency; stroke; stroke patient; walking; Carotid Stenosis; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Protein C Deficiency; Stroke; Ultrasonography, Doppler, Duplex
Type
journal article