|Title:||Right or left? Side selection for a totally implantable vascular access device: A randomised observational study||Authors:||Lin, Wen Ying
Lin, Chih Peng
Hsu, Chih Hung
Lee, Ying Hui
Lin, Yi Ting
Hsu, Meng Chi
Shao, Yu Yun
|Keywords:||cancer | catheter-related infection | central catheter | thrombosis||Issue Date:||26-Sep-2017||Journal Volume:||117||Journal Issue:||7||Source:||British Journal of Cancer||Abstract:||
© 2017 Cancer Research UK. All rights reserved. Background:Totally implantable vascular access device (TIVAD)-related complications interfere in the anticancer treatment and increase medical expenses. We examined whether the implantation side of central line TIVADs is associated with the occurrence of thrombotic or occlusion events.Methods:We enrolled patients with cancer who required central line TIVADs and randomised them to receive the TIVAD implantation on either the left or right side. The primary endpoint was the occurrence of catheter-related thrombotic or occlusion events.Results:We randomised 240 patients, of which 235 received TIVAD implantation according to the protocol. In the per-protocol cohort, 117 and 118 patients received implantation on the left and right sides, respectively. Catheter-related thrombotic or occlusion events occurred in 9 (4%) patients, accounting for 0.065 events per 1000 catheter-days. Between the patients with left-and right-sided implantations, the occurrence rates (P=0.333) and the time from catheter implantation to the occurrence of thrombotic or occlusion events (P=0.328) were both similar. In the multivariate analysis, the side of implantation remained unassociated with the occurrence of thrombotic or occlusion events.Conclusions:The side of central line TIVAD implantation was not associated with the occurrence of catheter-related thrombotic or occlusion events in patients with cancer.
|Appears in Collections:||腫瘤醫學研究所|
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