https://scholars.lib.ntu.edu.tw/handle/123456789/484430
標題: | A newborn screening system based on service-oriented architecture embedded support vector machine | 作者: | Hsu, K.-P. Hsieh, S.-H. Hsieh, S.-L. Cheng, P.-H. Weng, Y.-C. Wu, J.-H. Lai, F. FEI-PEI LAI |
關鍵字: | Newborn screening; Service-Oriented Architecture; Support Vector Machine; Tandem mass spectrometry; Web services | 公開日期: | 2010 | 卷: | 34 | 期: | 5 | 起(迄)頁: | 899-907 | 來源出版物: | Journal of Medical Systems | 摘要: | The clinical symptoms of metabolic disorders are rarely apparent during the neonatal period, and if they are not treated earlier, irreversible damages, such as mental retardation or even death, may occur. Therefore, the practice of newborn screening is essential to prevent permanent disabilities in newborns. In the paper, we design, implement a newborn screening system using Support Vector Machine (SVM) classifications. By evaluating metabolic substances data collected from tandem mass spectrometry (MS/MS), we can interpret and determine whether a newborn has a metabolic disorder. In addition, National Taiwan University Hospital Information System (NTUHIS) has been developed and implemented to integrate heterogeneous platforms, protocols, databases as well as applications. To expedite adapting the diversities, we deploy Service-Oriented Architecture (SOA) concepts to the newborn screening system based on web services. The system can be embedded seamlessly into NTUHIS. ? 2009 Springer Science+Business Media, LLC. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/484430 | DOI: | 10.1007/s10916-009-9305-6 | SDG/關鍵字: | hospital information system; metabolic disorder; newborn disease; newborn screening; review; support vector machine; Taiwan; tandem mass spectrometry; university hospital; Artificial Intelligence; Computer Communication Networks; Data Mining; Hospital Information Systems; Humans; Infant, Newborn; Metabolism, Inborn Errors; Neonatal Screening; Systems Integration; Taiwan; Tandem Mass Spectrometry; Workflow |
顯示於: | 生醫電子與資訊學研究所 |
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