https://scholars.lib.ntu.edu.tw/handle/123456789/485706
標題: | Mathematical estimation and in vivo dose measurement for cone-beam computed tomography on prostate cancer patients | 作者: | Jeng S.-C. CHIAO-LING TSAI Chan W.-T. Tung C.-J. Wu J.-K. CHIA-HSIEN CHENG |
公開日期: | 2009 | 卷: | 92 | 期: | 1 | 起(迄)頁: | 57-61 | 來源出版物: | Radiotherapy and Oncology | 摘要: | Background and purpose: Cone-beam computed tomography (CBCT) increases the doses on normal tissues. Our study sought to develop a mathematical model that would provide an estimate of and verify in vivo rectal dose from CBCT in prostate cancer patients. Materials and methods: Thermoluminescent dosimeters (TLDs) and Rando phantoms were used to measure doses to the pelvic region. We used an endorectal balloon to measure rectal doses for 10 prostate cancer patients who underwent radiotherapy and for whom we were able to acquire CBCT images. A solid water phantom and TLDs were used to correlate the rectal doses with body thickness/widths. A mathematical method was established to simulate the dose to which the patient is exposed during CBCT for the determined body parameters. The estimated doses were compared with the measured doses to determine the effectiveness of the model. Results: The average measured rectal dose from CBCT was 2.8 ± 0.3 cGy. The mathematical method was able to predict the rectal dose, with the limits of agreement of -0.03 ± 0.18 cGy. The average difference between predictions and measurements was -1.1 ± 3.6%. Conclusion: Our mathematical model was effective in estimating the exposed dose from CBCT. ? 2009 Elsevier Ireland Ltd. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-66949147540&doi=10.1016%2fj.radonc.2009.03.010&partnerID=40&md5=2c51ac6c30d31091a7794d480ad752f1 https://scholars.lib.ntu.edu.tw/handle/123456789/485706 |
ISSN: | 0167-8140 | DOI: | 10.1016/j.radonc.2009.03.010 | SDG/關鍵字: | accuracy; article; balloon; cancer patient; cancer radiotherapy; cone beam computed tomography; controlled study; dosimetry; human; in vivo study; intermethod comparison; male; mathematical model; pelvis; phantom; priority journal; prostate cancer; radiation dose; radiation exposure; rectum; thermoluminescence dosimeter; Cone-Beam Computed Tomography; Humans; Male; Models, Theoretical; Phantoms, Imaging; Prostatic Neoplasms; Radiation Dosage; Rectum; Thermoluminescent Dosimetry |
顯示於: | 腫瘤醫學研究所 |
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