https://scholars.lib.ntu.edu.tw/handle/123456789/490892
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Mouri, Akihiro | en_US |
dc.contributor.author | Lee, Hsin-Jung | en_US |
dc.contributor.author | Mamiya, Takayoshi | en_US |
dc.contributor.author | Aoyama, Yuki | en_US |
dc.contributor.author | Matsumoto, Yurie | en_US |
dc.contributor.author | Kubota, Hisayoshi | en_US |
dc.contributor.author | Huang, Wei-Jan | en_US |
dc.contributor.author | LIH-CHU CHIOU | en_US |
dc.contributor.author | Nabeshima, Toshitaka | en_US |
dc.creator | Mouri, Akihiro;Lee, Hsin-Jung;Mamiya, Takayoshi;Aoyama, Yuki;Matsumoto, Yurie;Kubota, Hisayoshi;Huang, Wei-Jan;Lih-Chu Chiou;Nabeshima, Toshitaka | - |
dc.date.accessioned | 2020-05-06T02:08:43Z | - |
dc.date.available | 2020-05-06T02:08:43Z | - |
dc.date.issued | 2020-03-04 | - |
dc.identifier.issn | 0007-1188 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/490892 | - |
dc.description.abstract | Hispidulin is a flavonoid isolated from Clerodendrum inerme that was found to inhibit intractable motor tics. Previously, we found that hispidulin attenuates hyperlocomotion and the disrupted prepulse inhibition induced by methamphetamine and N-methyl-d-aspartate (NMDA) receptor antagonists, two phenotypes of schizophrenia resembling positive symptoms. Hispidulin can inhibit COMT, a dopamine-metabolizing enzyme in the prefrontal cortex (PFC) that is important for social interaction. Here, we investigated whether hispidulin would affect social withdrawal, one of the negative symptoms of schizophrenia. | en_US |
dc.language.iso | en | en_US |
dc.publisher | WILEY | en_US |
dc.relation.ispartof | British journal of pharmacology | en_US |
dc.title | Hispidulin attenuates the social withdrawal in isolated disrupted-in-schizophrenia-1 mutant and chronic phencyclidine-treated mice | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1111/bph.15043 | - |
dc.identifier.pmid | 32133633 | - |
dc.identifier.scopus | 2-s2.0-85082838622 | - |
dc.identifier.isi | WOS:000523216100001 | - |
dc.identifier.url | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85082838622&doi=10.1111%2fbph.15043&partnerID=40&md5=e9d8d93b28bd3e41de38dfef184de801 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Pharmacology | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.orcid | 0000-0001-5356-940X | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 腦與心智科學研究所 |
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