Simplified derivatization method for triclosan determination in personal care products by gas chromatography-mass spectrometry
Journal
Journal of the Chinese Chemical Society
Journal Volume
58
Journal Issue
1
Pages
49-52
Date Issued
2011
Author(s)
Abstract
Abstract An efficient and eco‐friendly injection‐port tert ‐butyldimethylsilylated (TBDMS) derivatization and gas chromatography‐mass spectrometry (GC‐MS) was developed to determine triclosan (TCS, an antibacterial agent) in the samples of toothpaste, liquid hand‐soap and facial cleansing cream. This on‐line derivatization coupled ultrasonic extraction provides sensitivity, fast and reproducible results for TCS analysis. The accuracy and precision of the method was evaluated. The developed method was successfully applied to determine the content of TCS in selected personal care products.
Abstract An efficient and eco‐friendly injection‐port tert ‐butyldimethylsilylated (TBDMS) derivatization and gas chromatography‐mass spectrometry (GC‐MS) was developed to determine triclosan (TCS, an antibacterial agent) in the samples of toothpaste, liquid hand‐soap and facial cleansing cream. This on‐line derivatization coupled ultrasonic extraction provides sensitivity, fast and reproducible results for TCS analysis. The accuracy and precision of the method was evaluated. The developed method was successfully applied to determine the content of TCS in selected personal care products.
Publisher
Chinese Chemical Society Taiwan
Type
journal article