https://scholars.lib.ntu.edu.tw/handle/123456789/493527
標題: | Perioperative management and outcomes of minimally invasive esophagectomy: Case study of a high-volume tertiary center in Taiwan | 作者: | Chang T. PO-NI HSIAO Tsai M.-Y. PEI-MING HUANG YA-JUNG CHENG |
關鍵字: | Esophageal neoplasms; Esophagectomy; Outcome assessment | 公開日期: | 2018 | 出版社: | AME Publishing Company | 卷: | 10 | 期: | 3 | 起(迄)頁: | 1670-1676 | 來源出版物: | Journal of Thoracic Disease | 摘要: | Background: Mortality and complication rates for surgical esophagectomy remain high despite progress in surgical techniques and perioperative care. Minimally invasive surgery and intraoperative goal-directed fluid management are gaining popularity in Taiwan; however, perioperative complications and shortterm outcomes have been rarely reported. In this retrospective study, we analyzed the surgical procedures performed as well as the perioperative outcomes and treatments after esophagectomy in a high-volume medical center in Taiwan. The goals of this study are to compare the complications and the following treatment between different surgical procedures and to analyze if any preoperative coexisting disease and anesthesia conduct might be associated with postoperative complications and hospitalization course. Methods: We retrospectively reviewed the data of all patients who had undergone esophagectomy and reconstruction in 2015. Patient characteristics, type of surgery performed, method of anesthesia, postoperative hospitalization course, and additional surgical interventions were reviewed and analyzed. Results: In total, 64 patients were included. Among them, 58 patients (90.6%) were reported squamous cell carcinoma, 33 patients (51.6%) received McKeown minimally invasive esophagectomy (MIE), and 20 (31.3%) received Ivor-Lewis MIE. The most common postoperative complications were pulmonary complications (18.7%), such as empyema and pleural effusion, dysrhythmias (14.1%), anastomosis leakage (14.1%), vocal cord paralysis (9.4%), gastric tube stenosis (4.7%), chyle leakage (4.7%), and acute kidney injury (AKI, 4.7%). Twenty-five percent of patients received secondary operative interventions for the aforementioned complications. Postoperative arrhythmia (P=0.042), pulmonary complications (P=0.009), and AKI (P=0.015) were significantly associated with prolonged intensive care unit (ICU) stays. Thirty-day and 90-day mortality rates were 3.1% and 4.7% respectively. Patients with preoperative arrhythmias have a higher risk of developing post-operative dysrhythmia (P=0.013) and lung complications (P=0.036). Patients with an underlying heart disease are at higher risk of post-op AKI (P=0.002) and second surgical intervention (P=0.013). Chronic kidney diseases are associated with post-op dysrhythmia (P=0.013), lung complications (P=0.036) and post-op AKI (P?0.01). Although McKeown MIE bore a significantly longer surgical time and higher intraoperatively-infused crystalloid than did Ivor Lewis MIE, there were no significant differences regarding postoperative cardiothoracic complications and patient outcomes. Conclusions: Postoperative outcomes of McKeown MIE and Ivor-Lewis MIE were comparable in our center and short term outcomes were similar to those in previous reports. However, despite neoadjuvant concurrent chemoradiation therapy (CCRT), the use of minimally invasive techniques, and well-controlled anesthesia, the incidence of perioperative complications remains high. Our results suggest that patients with preoperative comorbidity of arrhythmia, heart diseases, and CKD are associated with more common postoperative complications. Furthermore, postoperative dysrhythmias, pulmonary complications, and AKI warrant special anesthetic and surgical care to prevent prolonged ICU stay. ? Journal of Thoracic Disease. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045252756&doi=10.21037%2fjtd.2018.01.147&partnerID=40&md5=21974d61c4c071e70da6999ffa62fa32 https://scholars.lib.ntu.edu.tw/handle/123456789/493527 |
ISSN: | 2072-1439 | DOI: | 10.21037/jtd.2018.01.147 | SDG/關鍵字: | acute kidney failure; adult; anastomosis leakage; Article; case study; chronic kidney failure; chyle leakage; controlled study; crystalloid; disease association; empyema; esophagus cancer; esophagus resection; female; gastric tube necrosis; gastric tube stenosis; general anesthesia; heart arrhythmia; hospitalization; human; iatrogenic hypoparathyroidism; intensive care unit; Ivor Lewis minimally invasive esophagectomy; major clinical study; male; McKeown minimally invasive esophagectomy; mortality rate; operation duration; pleura effusion; postoperative complication; retrospective study; squamous cell carcinoma; surgical technique; Taiwan; tertiary care center; vocal cord paralysis |
顯示於: | 醫學系 |
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