https://scholars.lib.ntu.edu.tw/handle/123456789/496275
標題: | Thyroidectomy or radioiodine? The value of ultrasonography and cytology in the assessment of nodular lesions in graves' hyperthyroidism | 作者: | CHIH-YUAN WANG TIEN-JYUN CHANG TIEN-CHUN CHANG Hsiao Y.-L. Chen M.-H. Huang S.-H. |
公開日期: | 2001 | 卷: | 67 | 期: | 8 | 起(迄)頁: | 721-726 | 來源出版物: | American Surgeon | 摘要: | Although diffuse toxic goiter is a classical feature of Graves' disease (GD) nodular goiters are occasionally found in some patients. The aim of the present study was to investigate the ultrasonographic and corresponding cytological manifestations in GD patients with nodular lesions to decide on a therapeutic strategy. Twenty-seven consecutive GD patients with nodular goiter were included in this study (21 women and six men, mean age 41.2 years, range 22-77 years). All underwent thyroid ultrasonography and fine-needle aspiration cytology. Of the 27 patients eight underwent surgical intervention because papillary thyroid carcinoma or follicular neoplasm was diagnosed by cytology; five of these were shown to have papillary thyroid carcinomas. Ultrasonography revealed the malignant nodules to be hypoechogenic, heterogeneous, and with illdefined margins in four of these five thyroid cancers, whereas the remaining sonogram showed a cystic change and cauliflower-like tumor formation with microcalcification. The volume and maximal diameter of cancerous nodules were significantly larger than those of benign nodules. In conclusion our results reveal that ultrasonography and fine-needle aspiration cytology are reliable and quick methods for diagnosing nodular goiters in GD patients. If thyroid neoplasms are found ablative therapy with thyroidectomy is indicated instead of radioactive iodine. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035433095&partnerID=40&md5=ef30891da0913c32de06f02813d31bfc https://scholars.lib.ntu.edu.tw/handle/123456789/496275 |
ISSN: | 0003-1348 | SDG/關鍵字: | adult; aged; article; echography; female; Graves disease; human; male; middle aged; needle biopsy; nodular goiter; papillary carcinoma; pathology; scintiscanning; thyroid gland; thyroid tumor; thyroidectomy; Adult; Aged; Biopsy, Needle; Carcinoma, Papillary; Female; Goiter, Nodular; Graves Disease; Humans; Male; Middle Aged; Thyroid Gland; Thyroid Neoplasms; Thyroidectomy |
顯示於: | 醫學系 |
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