https://scholars.lib.ntu.edu.tw/handle/123456789/496725
標題: | Value of immunoperoxidase staining of thyroglobulin in fine needle aspiration cytology of thyroid diseases | 作者: | Tung C.-C. TIEN-CHUN CHANG Hsieh H.-C. |
關鍵字: | aspiration biopsy; immunoperoxidase techniques; thyroglobulin; thyroid diseases | 公開日期: | 1995 | 出版社: | S. Karger AG | 卷: | 39 | 期: | 3 | 起(迄)頁: | 396-401 | 來源出版物: | Acta Cytologica | 摘要: | To elucidate the value of thyroglobulin staining by the immunoperoxidase method in fine needle aspiration cytology of thyroid diseases, it was performed on fine needle aspiration smears of 57 cases of various thyroid diseases. Thirteen of 22 cases (59%) with benign nodular goiter were positive. Eight of 14 cases (57%) with papillary thyroid carcinoma were positive. Among these eight cases with positive staining, seven were at clinical stage II or less. Among the other six cases with negative staining, five cases were in clinical stage III or more. There was a significant relationship between clinical stage and thyroglobulin staining (P <.05). One of 10 cases with thyroid cysts was positive. One of four cases with anaplastic carcinoma was positive. One of two cases with follicular thyroid carcinoma was positive. Two cases of subacute thyroiditis were positive. One case of Hashimoto's thyroiditis was positive. Two cases of metastatic thyroid cancer from the ovary were negative. These results reveal that positive thyroglobulin staining was helpful in defining the source of tissue from the thyroid. However, negative staining could not definitively exclude a thyroid origin. Positive thyroglobulin staining in papillary thyroid carcinoma correlated with less advanced clinical stages. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029029168&partnerID=40&md5=03f4512c81f3deb77edf408dfc03b2c6 https://scholars.lib.ntu.edu.tw/handle/123456789/496725 |
ISSN: | 0001-5547 | SDG/關鍵字: | thyroglobulin; anaplastic carcinoma; article; aspiration biopsy; cancer staging; cytology; Hashimoto disease; human; human tissue; immunoperoxidase staining; major clinical study; metastasis; nodular goiter; priority journal; subacute thyroiditis; thyroid cyst; thyroid disease; thyroid follicular carcinoma; thyroid papillary carcinoma |
顯示於: | 醫學系 |
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