https://scholars.lib.ntu.edu.tw/handle/123456789/496851
標題: | The relation of serum leptin to body mass index and to serum cortisol in men with spinal cord injury | 作者: | TIEN-SHANG HUANG Wang Y.-H. SSU-YUAN CHEN |
公開日期: | 2000 | 出版社: | W.B. Saunders | 卷: | 81 | 期: | 12 | 起(迄)頁: | 1582-1586 | 來源出版物: | Archives of Physical Medicine and Rehabilitation | 摘要: | Objective: To investigate the relations among serum leptin, body mass index (BMI), and various hormone levels in men with spinal cord injury (SCI). Design: Cross-sectional. Setting: University hospital that is a tertiary referral center. Participants: Forty-seven men with traumatic neurologically complete SCI and 47 age- and BMI-matched male controls. Main Outcome Measures: Baseline levels of various hormones were measured in subjects with SCI. Serum leptin and cortisol levels and BMI were measured in both groups. Results: Serum leptin was significantly higher in the group with SCI than in the control group. A linear relation was found between serum leptin and BMI in both groups separately. A polynomial relation was found between serum leptin level and BMI in the group with SCI. A 'J' phenomenon is noted at the lowest BMI. Serum cortisol correlated significantly with serum leptin level in the group with SCI. Conclusion: Sympathetic denervation, peripheral nerve palsy, recurrent infections, and possible central neurotransmitter alterations after SCI may contribute to the elevation of serum leptin level in men with SCI. (C) 2000 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033663996&doi=10.1053%2fapmr.2000.9173&partnerID=40&md5=b25fc887a1d60bf9bf37bc73c996872d https://scholars.lib.ntu.edu.tw/handle/123456789/496851 |
ISSN: | 0003-9993 | DOI: | 10.1053/apmr.2000.9173 | SDG/關鍵字: | hydrocortisone; leptin; neurotransmitter; adult; article; body mass; clinical article; controlled study; denervation; hormone determination; human; hydrocortisone blood level; male; nerve paralysis; obesity; peripheral nerve; protein blood level; recurrent infection; spinal cord injury |
顯示於: | 醫學系 |
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