A portable micro gas chromatography system for volatile compounds detection with 15ppb of sensitivity
Journal
Digest of Technical Papers - IEEE International Solid-State Circuits Conference
Journal Volume
58
Pages
388-389
Date Issued
2015
Author(s)
Tzeng, T.-H.
Kuo, C.-Y.
Wang, S.-Y.
Huang, P.-K.
Kuo, P.-H.
Huang, Y.-M.
Hsieh, W.-C.
Yu, S.-A.
WEI-CHENG TIAN
Abstract
Existing non-invasive lung cancer diagnostic equipment has difficulty in detecting early stage lung cancer as abnormal tissue is smaller than 0.5cm in size. According to studies showing that volatile organic compounds (VOCs) from human breath gas can provide biomarkers for human disease, especially for lung cancer [1], a non-invasive method was developed to measure the exhaled air from cancer patients using chromatography-mass spectrometry (GC-MS). However, traditional GC-MS equipment is very expensive and requires specialists to operate. In this research we demonstrate a portable micro gas chromatography (μGC) system to overcome the limitations of conventional methods and realize small chips for big data. ? 2015 IEEE.
SDGs
Other Subjects
Biological organs; Biomarkers; Diagnosis; Diseases; Mass spectrometry; Noninvasive medical procedures; Volatile organic compounds; Abnormal tissues; Cancer patients; Chromatography-mass spectrometry; Conventional methods; Early-stage lung cancers; Micro-gas chromatography; Noninvasive methods; Volatile compounds; Gas chromatography
Type
conference paper