https://scholars.lib.ntu.edu.tw/handle/123456789/502949
Title: | Association between non-alcoholic fatty pancreatic disease (nafpd) and the metabolic syndrome: Case-control retrospective study | Authors: | WAN-CHEN WU CHIH-YUAN WANG |
Issue Date: | 2013 | Journal Volume: | 12 | Journal Issue: | 1 | Start page/Pages: | 77 | Source: | Cardiovascular Diabetology | Abstract: | Background: Fatty liver is associated with insulin resistance, dyslipidemia, and obesity and is therefore considered a phenotype of metabolic syndrome. However, less is known regarding the metabolic abnormalities associated with non-alcoholic fatty pancreatic disease (NAFPD; fatty pancreas). The present study was performed to ascertain whether fatty pancreas is associated with specific metabolic risk factors and with metabolic syndrome as defined by the Adult Treatment Panel III.Methods: Five-hundred-fifty-seven healthy and consecutive subjects without known hypertension or diabetes and who received a health investigation at the National Taiwan University Hospital Health Management Center were enrolled in this retrospective study. Fatty pancreas was diagnosed via trans-abdominal ultrasonographic findings.Results: Seventy-two (12.9%) subjects diagnosed with fatty pancreas comprised the fatty pancreas group, and remaining subjects comprised the normal pancreas group. The presence of various demographic and metabolic risk factors was recorded for all subjects, and the two groups were examined for statistically significant differences in these factors. As compared to the absence of fatty pancreas, the presence of the disease was associated with older age and with higher values for each of the following: BMI, abdominal girth/height, abdominal girth (both genders), fasting and postprandial blood glucose, HbA1c, total cholesterol, triglycerides, LDL-cholesterol, systolic blood pressure, and platelet count. In contrast to previously reported findings, serum amylase values were lower in the fatty pancreas as compared to the control group.Conclusion: The presence of fatty pancreas represents a meaningful manifestation of metabolic syndrome together with obesity. ? 2013 Wu and Wang; licensee BioMed Central Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877842142&doi=10.1186%2f1475-2840-12-77&partnerID=40&md5=ccc086b5910011ebcce8c8802a141c8f https://scholars.lib.ntu.edu.tw/handle/123456789/502949 |
ISSN: | 1475-2840 | DOI: | 10.1186/1475-2840-12-77 | SDG/Keyword: | glucose; cholesterol; glucose blood level; glycosylated hemoglobin; hemoglobin A1c protein, human; low density lipoprotein cholesterol; triacylglycerol; abdomen; adult; article; body height; body mass; case control study; controlled study; diet restriction; disease association; female; glucose blood level; human; major clinical study; male; metabolic syndrome X; nonalcoholic fatty pancreatic disease; pancreas disease; postprandial state; retrospective study; risk assessment; risk factor; age distribution; blood; blood pressure; diabetes mellitus; echography; intraabdominal fat; metabolic syndrome X; obesity; Obesity, Abdominal; pancreas; Pancreatic Diseases; Age Distribution; Blood Glucose; Blood Pressure; Body Mass Index; Case-Control Studies; Cholesterol; Cholesterol, LDL; Diabetes Mellitus; Hemoglobin A, Glycosylated; Intra-Abdominal Fat; Metabolic Syndrome X; Obesity; Obesity, Abdominal; Pancreas; Pancreatic Diseases; Retrospective Studies; Risk Factors; Triglycerides |
Appears in Collections: | 醫學系 |
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