https://scholars.lib.ntu.edu.tw/handle/123456789/502985
標題: | Prediction of diabetic nephropathy from the relationship between fatigue, sleep and quality of life | 作者: | Lien A.S.-Y. YI-DER JIANG Tsai J.-L. Hwang J.-S. Lin W.-C. |
公開日期: | 2020 | 出版社: | MDPI AG | 卷: | 10 | 期: | 9 | 起(迄)頁: | 3282 | 來源出版物: | Applied Sciences (Switzerland) | 摘要: | Fatigue and poor sleep quality are the most common clinical complaints of people with diabetes mellitus (DM). These complaints are early signs of DM and are closely related to diabetic control and the presence of complications, which lead to a decline in the quality of life. Therefore, an accurate measurement of the relationship between fatigue, sleep status, and the complication of DM nephropathy could lead to a specific definition of fatigue and an appropriate medical treatment. This study recruited 307 people with Type 2 diabetes from two medical centers in Northern Taiwan through a questionnaire survey and a retrospective investigation of medical records. In an attempt to identify the related factors and accurately predict diabetic nephropathy, we applied hybrid research methods, integrated biostatistics, and feature selection methods in data mining and machine learning to compare and verify the results. Consequently, the results demonstrated that patients with diabetic nephropathy have a higher fatigue level and Charlson comorbidity index (CCI) score than without neuropathy, the presence of neuropathy leads to poor sleep quality, lower quality of life, and poor metabolism. Furthermore, by considering feature selection in selecting representative features or variables, we achieved consistence results with a support vector machine (SVM) classifier and merely ten representative factors and a prediction accuracy as high as 74% in predicting the presence of diabetic nephropathy. ? 2020 by the authors. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085106083&doi=10.3390%2fapp10093282&partnerID=40&md5=ab33761c31826160c3a4d7e5f1830e5a https://scholars.lib.ntu.edu.tw/handle/123456789/502985 |
ISSN: | 2076-3417 | DOI: | 10.3390/app10093282 |
顯示於: | 醫學系 |
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