A case of transient existence of SARS-CoV-2 RNA in the respiratory tract with the absence of anti-SARS-CoV-2 antibody response
Journal
International Journal of Infectious Diseases
Journal Volume
96
Pages
464-466
Date Issued
2020
Author(s)
Abstract
We report the case of a patient who had travelled to Japan and who presented mild respiratory symptoms during the COVID-19 outbreak period. There was transient existence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in his oropharynx. The RNA was absent in the six respiratory specimens that were subsequently tested. An anti-SARS-CoV-2 antibody response was absent in the acute and convalescent sera. The reported case indicates that transient colonization of SARS-CoV-2 in the upper respiratory tract is possible without inciting any antibody response against the virus. ? 2020 The Author(s)
SDGs
Other Subjects
antibody; hydroxychloroquine; immunoglobulin G; immunoglobulin M; nucleocapsid protein antibody; unclassified drug; virus RNA; virus antibody; virus RNA; adult; antibody response; Article; case report; clinical article; coronavirus disease 2019; coughing; E gene; human; leukocyte count; male; microbial colonization; oropharynx; rdrp2 gene; real time reverse transcription polymerase chain reaction; Severe acute respiratory syndrome coronavirus 2; throat culture; virus gene; Betacoronavirus; Coronavirus infection; epidemic; genetics; immunology; Japan; pandemic; respiratory system; virus pneumonia; Adult; Antibodies, Viral; Betacoronavirus; Coronavirus Infections; Disease Outbreaks; Humans; Japan; Male; Pandemics; Pneumonia, Viral; Respiratory System; RNA, Viral
Type
journal article