Signal analysis and liver tumor discrimination by using a high-Tc SQUID-based low-field NMR system in hospital
Journal
IEEE Transactions on Applied Superconductivity
Journal Volume
25
Journal Issue
3
Pages
7012140
Date Issued
2015
Author(s)
Abstract
In this paper, a high-T c SQUID-based nuclear magnetic resonance (NMR) spectrometer was set up in National Taiwan University Hospital to discriminate liver tumor. In order to overcome the surrounding noise, a four-layer Al shielded box and a cylindrical magnetic shield were employed to avoid the electromagnetic noise in the coils part and the SQUID part, respectively. For NMR measurement, the larmor frequency is varying with time due to the variation of static field in hospital. Therefore, the time-domain frequency adjusted average method guided by a fluxgate was used to correct the frequency variation and average the NMR signal in the time domain. For tumor discrimination, the T 1 relaxation times of normal tissue and tumor tissue were demonstrated. Our high-T c SQUID-based low-field MRI system shows the feasibility for biomedical application in a clinic environment.
SDGs
Publisher
Institute of Electrical and Electronics Engineers Inc.
Type
journal article