https://scholars.lib.ntu.edu.tw/handle/123456789/504758
標題: | Probing the tratis of epithelial-mesenchymal transition in a microfluidic device | 作者: | Kuo C.T. Chiang C.L. RUBY YUN-JU HUANG Lee H. Wo A.M. |
關鍵字: | EMT; Microfluidic; Pipette-friendly; Tumor spheroid | 公開日期: | 2011 | 卷: | 1 | 起(迄)頁: | 145-147 | 來源出版物: | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 | 摘要: | The epithelial to mesenchymal transition (EMT) plays a crucial role during cancer invasion and metastasis [1, 2]. In this paper, we present a microfluidic device that can facilitate probing the traits of EMT in micrometer-scale environments. Furthermore, we show that epithelial cancer cells can grow to a tumor spheroid in the device, acquire properties of mesenchymal cells, and have an increased ability of migration, comparing with native cancer cells. The microfluidic device requires no external pumping systems yet being pipette-friendly in usage. Copyright ? (2011) by the Chemical and Biological Microsystems Society. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870871948&partnerID=40&md5=264053abb94441a3cf9f3edd17d805ea https://scholars.lib.ntu.edu.tw/handle/123456789/504758 |
ISSN: | #VALUE! | SDG/關鍵字: | EMT; Epithelial cancer cells; Epithelial to Mesenchymal transitions; Epithelial-mesenchymal transition; Mesenchymal cells; Micro-fluidic devices; Pipette-friendly; Tumor spheroid; Microfluidics; Tumors; Fluidic devices |
顯示於: | 醫學系 |
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