https://scholars.lib.ntu.edu.tw/handle/123456789/504911
Title: | Detoxification of high-dose zolpidem using cross-titration with an adequate equivalent dose of diazepam | Authors: | Chen S.-C. HSI-CHUNG CHEN Shih-Cheng Liao Tseng M.C.M. MING-BEEN LEE |
Issue Date: | 2012 | Publisher: | Elsevier Inc. | Journal Volume: | 34 | Journal Issue: | 2 | Start page/Pages: | 21000000-2100000000 | Source: | General Hospital Psychiatry | Abstract: | Background: There have been numerous case reports of zolpidem abuse and dependence in the recent decade, giving rise to a focus on adverse withdrawal events such as seizure. No standard detoxification regimen has been proposed to date, despite the similarity of effects of zolpidem and benzodiazepines at high doses. Case Descriptions: We describe the results, in a 53-year-old female patient, of undergoing three different zolpidem detoxification programs. Conclusions: Because of her experiences, we recommend using the cross-titration strategy with an adequate equivalent dose of diazepam. ? 2012 Elsevier Inc.. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857371407&doi=10.1016%2fj.genhosppsych.2011.09.012&partnerID=40&md5=3e73d0a2dff5bd721a1d12359b98ca15 https://scholars.lib.ntu.edu.tw/handle/123456789/504911 |
ISSN: | 0163-8343 | DOI: | 10.1016/j.genhosppsych.2011.09.012 | SDG/Keyword: | benzodiazepine; clonazepam; diazepam; flunitrazepam; paroxetine; quetiapine; sertraline; zolpidem; adult; anxiety; article; bedtime dosage; case report; drug absorption; drug abuse; drug dependence; drug detoxification; drug dose escalation; drug dose increase; drug dose reduction; drug dose titration; drug effect; drug half life; drug megadose; drug tolerability; drug withdrawal; female; heart palpitation; human; insomnia; irritability; loading drug dose; psychological aspect; seizure; side effect; tremor; withdrawal syndrome |
Appears in Collections: | 醫學系 |
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