https://scholars.lib.ntu.edu.tw/handle/123456789/504912
Title: | Recurrent escitalopram-induced hyponatremia in an elderly woman with dementia with Lewy bodies | Authors: | Tsai P.-H. HSI-CHUNG CHEN Shih-Cheng Liao Tseng M.C.M. MING-BEEN LEE |
Issue Date: | 2012 | Publisher: | Elsevier Inc. | Journal Volume: | 34 | Journal Issue: | 1 | Start page/Pages: | 10100000-1010000000 | Source: | General Hospital Psychiatry | Abstract: | We report the development of hyponatremia following initiation of escitalopram therapy in a 73-year-old woman. The patient, with a history of dementia with Lewy bodies, had presented with multiple neuropsychiatric symptoms. Within 2 months of escitalopram, she became delirious with a serum sodium level of 122 mmol/L. After discontinuation of escitalopram, her consciousness improved with resolving hyponatremia. Delirium and hyponatremia (122 mmol/L), however, recurred after escitalopram was rechallenged. Apart from eight other cases to date, this is the only one with recurrent hyponatremia. Rechallenge of the same antidepressant is discouraged especially in patients at risk of developing hyponatremia. ? 2012 Elsevier Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84855348858&doi=10.1016%2fj.genhosppsych.2011.06.007&partnerID=40&md5=3e371396f615435a88282efc4f4135f9 https://scholars.lib.ntu.edu.tw/handle/123456789/504912 |
ISSN: | 0163-8343 | DOI: | 10.1016/j.genhosppsych.2011.06.007 | SDG/Keyword: | bethanechol; carbidopa plus levodopa; cefazolin; escitalopram; quetiapine; tamsulosin; trihexyphenidyl; aged; article; atrophy; case report; clinical feature; delirium; delusion; diffuse Lewy body disease; drug induced disease; drug withdrawal; dysphoria; electroencephalography; Escherichia coli; female; human; hyponatremia; inappropriate vasopressin secretion; leukoaraiosis; low drug dose; memory disorder; nuclear magnetic resonance imaging; overactive bladder; parkinsonism; pyuria; senile cataract; sleep disorder; sodium blood level; treatment outcome; urinalysis; urinary tract infection |
Appears in Collections: | 醫學系 |
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