|Title:||Multicenter study of azole-resistant aspergillus fumigatus clinical isolates, Taiwan||Authors:||Wu, Chi Jung
Liu, Wei Lun
Lai, Chih Cheng
Chao, Chien Ming
Ko, Wen Chien
Wang, Hsuan Chen
Dai, Ching Tzu
Hsieh, Ming I.
Choi, Pui Ching
Yang, Jia Ling
|Issue Date:||1-Apr-2020||Publisher:||CENTERS DISEASE CONTROL & PREVENTION||Journal Volume:||26||Journal Issue:||4||Start page/Pages:||806||Source:||Emerging Infectious Diseases||Abstract:||
© 2020 Centers for Disease Control and Prevention (CDC). All rights reserved. In a multicenter study, we determined a prevalence rate of 4% for azole-resistant Aspergillus fumigatus in Taiwan. Resistance emerged mainly from the environment (TR34/ L98H, TR34/L98H/S297T/F495I, and TR46/Y121F/T289A mutations) but occasionally during azole treatment. A high mortality rate observed for azole-resistant aspergillosis necessitates diagnostic stewardship in healthcare and antifungal stewardship in the environment.
|Appears in Collections:||醫學院附設醫院 (臺大醫院)|
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