https://scholars.lib.ntu.edu.tw/handle/123456789/510019| Title: | Multicenter study of azole-resistant aspergillus fumigatus clinical isolates, Taiwan | Authors: | Wu, Chi Jung Liu, Wei Lun Lai, Chih Cheng Chao, Chien Ming Ko, Wen Chien Wang, Hsuan Chen Dai, Ching Tzu Hsieh, Ming I. Choi, Pui Ching Yang, Jia Ling YEE-CHUN CHEN |
Issue Date: | 1-Apr-2020 | Publisher: | CENTERS DISEASE CONTROL & PREVENTION | Journal Volume: | 26 | Journal Issue: | 4 | Start page/Pages: | 806 | Source: | Emerging Infectious Diseases | Abstract: | © 2020 Centers for Disease Control and Prevention (CDC). All rights reserved. In a multicenter study, we determined a prevalence rate of 4% for azole-resistant Aspergillus fumigatus in Taiwan. Resistance emerged mainly from the environment (TR34/ L98H, TR34/L98H/S297T/F495I, and TR46/Y121F/T289A mutations) but occasionally during azole treatment. A high mortality rate observed for azole-resistant aspergillosis necessitates diagnostic stewardship in healthcare and antifungal stewardship in the environment. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/510019 | ISSN: | 10806040 | DOI: | 10.3201/eid2604.190840 |
| Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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