Retropalatal Müller grade is associated with the severity of obstructive sleep apnea in non-obese Asian patients: Retropalatal Müller grade and OSA in non-obese
Journal
Sleep and Breathing
Journal Volume
15
Journal Issue
4
Pages
799-807
Date Issued
2011
Author(s)
Abstract
Purpose: The aim of this study was to investigate whether physical evaluations could be used for predicting the presence and severity of obstructive sleep apnea (OSA) in non-obese snoring patients. Methods: This is a retrospective study, and a total of 244 nonobese (body mass index, BMI, <27 kg/m 2) snoring patients (178 men and 66 women; mean age=43.1±12.1 years) were included. Each patient underwent polysomnography and a thorough physical examination, including flexible nasopharyngoscopy and M?ller maneuver. Patients were divided into four groups based on apnea-hypopnea index (AHI) scores: normal (simple snoring), AHI<5; mild OSA, 5≦AHI<15; moderate OSA, 15≦AHI<30; severe OSA, AHI≧30. Logistic regression was used to identify risk factors for OSA severity. Results: Fifty-nine patients (24%) were simple snorers. The prevalence of sleep apnea (mild, moderate, or severe OSA) for our non-obese snoring patients was 76%. Univariate logistic analyses showed that higher BMI, male gender and retropalatal M?ller grades were significantly associated with OSA severity. Multivariate logistic regression analysis identified male gender and retropalatal M?ller grade as risk factors for OSA in non-obese snoring patients. Conclusions: Physical examination may be useful for studying the upper airway in non-obese snoring patients. Flexible nasopharyngoscopy with M?ller maneuver appears to be useful for evaluating the severity of OSA in nonobese patients. Retropalatal M?ller grade is highly related to both the presence and severity of OSA, particularly in males. ? Springer-Verlag 2010.
SDGs
Other Subjects
adult; article; Asian; body mass; controlled study; disease severity; endoscopy; female; human; major clinical study; male; muller maneuver; multivariate logistic regression analysis; physical examination; polysomnography; prediction; priority journal; retrospective study; scoring system; sex difference; sleep apnea syndrome; snoring; airway obstruction; classification; computer assisted diagnosis; cultural factor; laryngoscopy; methodology; middle aged; prognosis; receiver operating characteristic; reference value; reproducibility; sleep apnea syndrome; statistics; Adult; Airway Obstruction; Body Mass Index; Cross-Cultural Comparison; Female; Humans; Image Interpretation, Computer-Assisted; Laryngoscopy; Male; Middle Aged; Prognosis; Reference Values; Reproducibility of Results; ROC Curve; Sleep Apnea, Obstructive
Type
journal article