Suicide and chronic kidney disease: A case-control study
Journal
Nephrology Dialysis Transplantation
Journal Volume
32
Journal Issue
9
Pages
1524-1529
Date Issued
2017
Author(s)
Abstract
Background. The association of chronic kidney disease (CKD) and dialysis with suicide is not well established. The objectives of this study were to assess the association of suicide with CKD and dialysis and investigate whether differences exist between dialysis modalities or the durations of dialysis. Methods. Data were obtained from the Taiwan National Health Insurance Research Database. A total of 51 642 patients who died from suicide between 2000 and 2012 and 206 568 living control patients matched by age, gender and residency area were examined. Known risk factors included sociodemographic characteristics, physical comorbidities and psychiatric disorders, which were controlled for as covariates in the analysis. The crude odds ratios (ORs) and adjusted ORs (aORs) for various risk factors were obtained using conditional logistic regression. Results. After potential confounders were controlled for, CKD was significantly associated with an increased risk of suicide [aOR = 1.25, 95% confidence interval (CI) = 1.17-1.34]. Endstage renal disease patients on haemodialysis (HD) had an increased risk of suicide compared with controls (aOR = 3.35, 95% CI = 3.02-3.72). Moreover, patients who initially underwent dialysis within 0-3 months had a significantly increased risk of suicide (aOR = 20.26, 95% CI = 15.99-25.67). Conclusions. CKD and HD are positively associated with suicide. Suicide is preventable; therefore, assessingmental and physical disorders is essential and recommended to all physicians, particularly those treating patients in the early phase of HD. ? 2017 The Author.
Subjects
CKD; Dialysis; Haemodialysis; Suicide
SDGs
Other Subjects
adult; age; aged; anxiety disorder; Article; case control study; cerebrovascular disease; chronic kidney failure; chronic obstructive lung disease; comorbidity; controlled study; demography; disease association; drug dependence; end stage renal disease; female; gender; hemodialysis; hemodialysis patient; hepatitis C; human; hypertension; major clinical study; male; malignant neoplasm; mental disease; middle aged; mood disorder; priority journal; psychosis; risk factor; social aspect; suicide; treatment duration; young adult; adolescent; chronic kidney failure; factual database; longitudinal study; mental disease; psychology; suicide; Taiwan; trends; Adolescent; Adult; Aged; Case-Control Studies; Comorbidity; Databases, Factual; Female; Humans; Longitudinal Studies; Male; Mental Disorders; Middle Aged; Renal Dialysis; Renal Insufficiency, Chronic; Risk Factors; Suicide; Taiwan; Young Adult
Type
journal article