https://scholars.lib.ntu.edu.tw/handle/123456789/511090
標題: | Surgical treatment of gastric adenocarcinoma: the role of lymph node dissection. | 作者: | WEN-JENG LEE Hsu F.-C. CHIA-TUNG SHUN PO-HUANG LEE Yu S.-C. KING-JEN CHANG Wang S.-M. Wei T.-C. WEN-CHUNG LEE Chen K.-M. |
公開日期: | 1995 | 卷: | 94 | 期: | 5 | 起(迄)頁: | 221-227 | 來源出版物: | Journal of the Formosan Medical Association = Taiwan yi zhi | 摘要: | In this retrospective study, 652 patients who had curative resections for gastric cancer from 1977 to 1991 were reviewed to evaluate improvements in gastric cancer surgery and the influence of the extent of lymphadenectomy on survival. The patients were grouped into three time periods: 1977 to 1981, 1982 to 1986 and 1987 to 1991. The percentage of patients with early gastric cancer increased from 17.7% during 1977 to 1981, to 24.3% during 1987 to 1991. The average number of dissected lymph nodes was 7.5 +/- 8.1 during 1977 to 1981 and 16.4 +/- 10.3 during 1987 to 1991, when more radical lymphadenectomy was adopted. Total gastrectomies increased from 10.9% to 25.9% in the same time periods while combined visceral resections increased from 26.7% to 38.1%. Operative mortality decreased from 5.0% to 1.7%. The overall 5-year survival rate increased from 34.8% to 59.4%. In subgroup analysis, significant improvement of the 5-year survival rate was noted in the following groups: patients with stage I, II and III tumors but not stage IV; both proximal and distally located tumors; tumors with or without lymph node metastases; T1 and T2 but not in T3 and T4 (cancer invasion beyond the serosa). The decreased surgical mortality in recent years suggests that curative resection with extensive lymph node dissection can now be safely performed. Radical gastrectomy with extended lymphadenectomy may be adopted in gastric cancer resection for better control of regional disease. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/511090 | ISSN: | 0929-6646 | SDG/關鍵字: | adenocarcinoma; analysis of variance; article; female; gastrectomy; human; lymphadenectomy; male; methodology; middle aged; mortality; pathology; retrospective study; stomach tumor; survival rate; Taiwan; Adenocarcinoma; Analysis of Variance; Female; Gastrectomy; Humans; Lymph Node Excision; Male; Middle Aged; Retrospective Studies; Stomach Neoplasms; Survival Rate; Taiwan |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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