https://scholars.lib.ntu.edu.tw/handle/123456789/511275
標題: | Paget's disease of the bone: A case report | 作者: | Chen W.-T. TIFFANY TING-FANG SHIH Shih L.-S. Lo S.-Y. Chen R.-C. Tu H.-Y. |
關鍵字: | Paget's disease Taiwan | 公開日期: | 2001 | 卷: | 100 | 期: | 2 | 起(迄)頁: | 137-141 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Paget's disease of bone is rare in Asia. We report a case of Paget's disease in a 58-year-old Taiwanese man who was admitted with a 3-month history of bilateral numbness in the buttock region. Laboratory data disclosed an elevated serum alkaline phosphatase level (510 U/L). Plain radiographs of the lumber spine showed generalized increased density at the third lumbar vertebra, associated with cortical thickening, loss of cortico-cancellous definition, and increased anteroposterior diameter. The T1-weighted magnetic resonance image of the lumbar spine showed diffuse, heterogenous low signal intensity at the third lumbar vertebral body, pedicle, laminae, and spinal process; these areas showed mixed high and low signal intensity on the T2-weighted image. Technetium-99m bone scan revealed abnormal uptake in the involved vertebra. Histologic examination of the third lumbar spinal process confirmed the diagnosis of Paget's disease of bone. The patient remained well during a follow-up period of 6 months. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/511275 | ISSN: | 0929-6646 | SDG/關鍵字: | alkaline phosphatase; gadolinium pentetate; technetium 99m; adult; alkaline phosphatase blood level; article; biopsy; bone density; bone scintiscanning; buttock; case report; contrast enhancement; cortical bone; histopathology; human; lumbar spine; male; nuclear magnetic resonance imaging; osteoblast; osteoclast; Paget bone disease; paresthesia; spine radiography; Taiwan; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Osteitis Deformans |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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