https://scholars.lib.ntu.edu.tw/handle/123456789/511678
標題: | A case report of legionaire's disease in an immunocompromised patient | 作者: | WAN-HSUAN LEE Lin W.-P. YING-CHUN CHIEN CHIEH-YU SHEN YEE-CHUN CHEN |
公開日期: | 2017 | 出版社: | Society of Internal Medicine of Taiwan | 卷: | 28 | 期: | 5 | 起(迄)頁: | 304-308 | 來源出版物: | Journal of Internal Medicine of Taiwan | 摘要: | Legionella pneumophila is one of the most important pathogens that can cause severe community-acquired pneumonia. It may present as Pontiac fever, a mild and self-limiting disease, or Legionnaire's disease, which usually causes severe pneumonia with high mortality. Although there are several unique features of Legionnaire's disease, it remains a challenge to differentiate Legionnaire's disease from influenza pneumonia due to the clinical and radiological similarities or overlapping between these two diseases. However, early initiation of appropriate therapy reduces mortality. Here, we present the case of a 48-year-old female patient, who had systemic lupus erythematous and underwent long-term steroid treatment. She presented with severe community-acquired pneumonia during the influenza season. Influenza pneumonia was suspected initially according to her travel history and clinical presentation, but Legionnaire's disease was confirmed according to urine antigen assay and sputum culture. The patient died of multiple organ failure in three weeks despite aggressive antibiotic treatment. This article reviewed the clinical features of legionellosis in both immunocompetent and immunocompromised hosts, and compared the difference in clinical presentation between legionellosis and influenza infection. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85038555600&doi=10.6314%2fJIMT.2017.28%285%29.06&partnerID=40&md5=3734a47fabf98d7b94f41e753b9c0c58 https://scholars.lib.ntu.edu.tw/handle/123456789/511678 |
ISSN: | 1016-7390 | DOI: | 10.6314/JIMT.2017.28(5).06 | SDG/關鍵字: | antibiotic agent; steroid; adult; antibiotic therapy; Article; case report; cause of death; clinical article; clinical feature; community acquired pneumonia; female; human; immunoassay; immunocompromised patient; influenza; legionnaire disease; middle aged; multiple organ failure; sputum culture; steroid therapy; systemic lupus erythematosus |
顯示於: | 醫學系 |
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