https://scholars.lib.ntu.edu.tw/handle/123456789/512487
標題: | Mycobacterial peritonitis: Difference between non-tuberculous mycobacteria and Mycobacterium tuberculosis | 作者: | CHIN-CHUNG SHU JANN-TAY WANG JANN-YUAN WANG CHONG-JEN YU LI-NA LEE |
公開日期: | 2012 | 出版社: | Blackwell Publishing Ltd | 卷: | 18 | 期: | 3 | 起(迄)頁: | 246-252 | 來源出版物: | Clinical Microbiology and Infection | 摘要: | Unlike tuberculous peritonitis, peritonitis due to non-tuberculous mycobacteria (NTM) has unclear clinical manifestations. This study aimed to clarify the clinical manifestations and laboratory results of NTM peritonitis and compare it to tuberculous peritonitis. This retrospective study was conducted from 2000 to 2008 in a medical centre in Taiwan. Patients with mycobacteria isolated from ascites were identified and compared according to causative pathogens (Mycobacterium tuberculosis or NTM). Those with NTM peritonitis were further classified into the 'probable' and 'possible' groups based on diagnostic evidence. Twenty-five patients with NTM peritonitis and 65 with tuberculous peritonitis were reviewed. Mycobacterium avium complex was the most common NTM pathogen (52%). There was no obvious difference between the 'probable' and 'possible' NTM peritonitis groups regarding age and laboratory data. Patients with NTM peritonitis and those with tuberculous peritonitis had no differences in age or gender but varied in symptoms and serum laboratory data. NTM peritonitis was 100% associated with underlying co-morbidities and had lower proportions of lymphocytes and albumin level in ascites. Twelve (48%) NTM peritonitis and 21 (32%) tuberculous peritonitis patients died during the 6-month follow-up. Anti-mycobacterial treatment, but not mycobacterial species, was correlated with better 6-month survival. In Taiwan, NTM is responsible for 28% of mycobacterial peritonitis cases, which have a poor prognosis if untreated. There are some differences in clinical manifestations between NTM and tuberculous peritonitis. NTM peritonitis should be considered in patients with peritonitis but without causative microorganisms identified other than NTM. ? 2011 The Authors. Clinical Microbiology and Infection ? 2011 European Society of Clinical Microbiology and Infectious Diseases. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857642878&doi=10.1111%2fj.1469-0691.2011.03547.x&partnerID=40&md5=cac6722a0d2e05f4af0e9be3e838e8e4 https://scholars.lib.ntu.edu.tw/handle/123456789/512487 |
ISSN: | 1198-743X | DOI: | 10.1111/j.1469-0691.2011.03547.x | SDG/關鍵字: | albumin; antimycobacterial agent; abdominal pain; alcoholism; article; ascites; atypical Mycobacterium; autoimmune disease; bacterial peritonitis; bacterium identification; chronic kidney disease; clinical feature; diabetes mellitus; evaluation and follow up; female; fever; gastrointestinal symptom; human; liver cirrhosis; lymphocyte; major clinical study; male; malignant neoplastic disease; Mycobacterium avium; peritoneal dialysis; priority journal; retrospective study; stomach distension; survival rate; Taiwan; Corynebacterineae; Mycobacterium avium complex; Mycobacterium tuberculosis |
顯示於: | 醫學系 |
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