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  4. Taiwan aneurysm registry: Multivariate analysis of two-month, one-year, and two-year outcomes after endovascular and microsurgical treatment of ruptured aneurysms
 
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Taiwan aneurysm registry: Multivariate analysis of two-month, one-year, and two-year outcomes after endovascular and microsurgical treatment of ruptured aneurysms

Journal
Interventional Neuroradiology
Journal Volume
19
Journal Issue
1
Pages
35-42
Date Issued
2013
Author(s)
HON-MAN LIU  
Wong H.-F.
Lee K.-W.
YONG-KWANG TU  
Yeh Y.-S.
Chou C.-W.
Wang Y.-H.
Chen Y.-L.
Lo Y.-L.
Hsieh T.-C.
Wang Y.-C.
Lin T.-K.
DAR-MING LAI  
Chen W.-L.
Tseng H.-M.
Li C.-W.
DOI
10.1177/159101991301900105
URI
https://scholars.lib.ntu.edu.tw/handle/123456789/513373
Abstract
We compared the outcomes of endovascular coiling with microsurgical clipping of aneurysms in a Taiwanese population. In an ambi-directional cohort design, patient baseline characteristics and clinical course after treatment for ruptured subarachnoid aneurysm were abstracted from medical records from three hospitals to examine and compare differences in post-operative outcomes between those treated with endovascular coiling and those treated with microsurgical clipping. Outcomes were measured, using the modified Rankin scale, two months, one year and two years postoperatively. Of the 642 patients enrolled in the study, 281 underwent endovascular treatment and 361 underwent neurosurgery. The demographics and baseline characteristics of two groups were comparable except for a larger maximum target aneurysm lumen size (p=0.02) in the endovascular group. Patients who underwent the endovascular procedure tended to have a better quality of life than those who had neurosurgery (p<0.01). When the severity of symptom data was pooled into two groups (Rankin values 0-2 and 3-6) a statistically significant relationship was found between the severity of symptoms and age, Hunt and Hess grade, number of target aneurysms detected, and log of maximum target aneurysm lumen size (all p?0.01). After controlling for potential confounding factors and using the lumped Rankin outcome data, no significant difference in outcome was found between the two procedures at either time point. Our study indicated that endovascular coiling achieves results comparable to surgical clipping for patients with ruptured subarachnoid aneurysms in a Taiwanese population.
SDGs

[SDGs]SDG3

Other Subjects
adult; aneurysm clip; aneurysm rupture; article; artificial embolism; controlled study; disease course; disease severity; endovascular coiling; female; human; major clinical study; male; microsurgery; multivariate analysis; neurosurgery; postoperative period; quality of life; Rankin scale; subarachnoid aneurysm rupture; Taiwan; treatment outcome
Type
journal article

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To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

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