Chronic schizophrenia comorbid with neuropsychiatric system lupus erythematosus
Journal
Taiwanese Journal of Psychiatry
Journal Volume
26
Journal Issue
1
Pages
52-57
Date Issued
2012
Author(s)
Abstract
Background: The neuropsychiatric events are frequently encountered in patients with systemic lupus erythematosus (SLE). The psychotic symptoms and cognitive dysfunctions are relatively common in SLE with central nervous system (CNS) involvement. Case Report: We present a patient with SLE with CNS involvement, who has also carried a diagnosis of schizophrenia for nine years. The presentation of progressive cognitive impairment suggested the diagnosis of SLE with CNS involvement. The result of the neuropsychological assessment showed great improvement after a six-month immunosuppressant therapy, especially in the dimensions of verbal and visual memory. The brain perfusion scan also showed the finding of remarkable improvement after treatment. Conclusion: This case shows the differences and complex presentations in psychopathology, neuropsychological tests, and brain imaging in those two diseases. Clinicians should be alert for considering other organic causes for progressive cognitive impairments in the course of chronic schizophrenia.
SDGs
Type
journal article