Skip navigation
  • 中文
  • English

DSpace CRIS

  • DSpace logo
  • Home
  • Organizations
  • Researchers
  • Research Outputs
  • Explore by
    • Organizations
    • Researchers
    • Research Outputs
  • Academic & Publications
  • Sign in
  • 中文
  • English
  1. NTU Scholars
  2. 醫學院
  3. 醫學院附設醫院 (臺大醫院)
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/514549
Title: High prevalence of asymptomatically poor muscle perfusion of lower extremities measured in type II diabetes patients with abnormal myocardial perfusion
Authors: Lin C.-C.
Ding H.-J.
RUOH-FANG YEN 
Wang J.-J.
Ho S.-T.
Kao A.
Issue Date: 2003
Journal Volume: 17
Journal Issue: 6
Start page/Pages: 365-368
Source: Journal of Diabetes and its Complications
Abstract: 
Foot problems are the most common cause of hospital admission in patients with type II diabetes mellitus (DM). Poor muscle perfusion of lower extremities is thought to be the major component in the pathogenesis of foot problems. Therefore, it is important and interesting to investigate if high prevalence of poor muscle perfusion of lower extremities in type II DM patients with abnormal myocardial perfusion and more cardiovascular risk factors. We used a well-established and noninvasive radionuclide method (Xe-133 muscle washout) to objectively evaluate the anterior tibial muscle perfusion of 60 type II DM male patients without symptoms/signs of peripheral vascular disease (PVD) in the lower extremities. The patients were separated into groups according to the myocardial perfusion imaging results and cardiovascular risk factor survey. Meanwhile, 30 normal male controls with a matched age distribution were also included for comparison. The muscle perfusions were of significant difference (P-values <.05) between (1) 60 type II DM patients (1.84±0.43 ml/100 g/min) and 30 normal controls (2.95±0.52 ml/100 g/min), (2) 24 patients with abnormal myocardial perfusion (1.31±0.45 ml/100 g/min) and 36 patients with normal myocardial perfusion (2.24±0.48 ml/100 g/min), as well as (3) 28 patients with more cardiovascular risk factors (1.33±0.46 ml/100 g/min) and 22 patient with less cardiovascular risk factors (2.22±0.49 ml/100 g/min). Based on Xe-133 muscle washout method, we concluded that the muscle perfusion in the lower extremities of type II DM patients without symptoms/signs of PVD is significantly decreased and related to abnormal myocardial perfusion and more cardiovascular risk factors. ? 2003 Elsevier Inc. All rights reserved.
URI: https://scholars.lib.ntu.edu.tw/handle/123456789/514549
ISSN: 1056-8727
DOI: 10.1016/S1056-8727(02)00244-1
SDG/Keyword: radioisotope; technetium 99m; xenon 133; adult; aged; arteriography; article; cardiovascular risk; cigarette smoking; clinical study; controlled study; creatinine clearance; disease duration; dyslipidemia; evaluation; heart muscle perfusion; human; hypertension; leg muscle; major clinical study; male; muscle perfusion; non insulin dependent diabetes mellitus; peripheral vascular disease; prevalence; priority journal; risk assessment; risk factor; statistical analysis; statistical significance; symptomatology; tibialis anterior muscle
[SDGs]SDG3
Appears in Collections:醫學院附設醫院 (臺大醫院)

Show full item record

SCOPUSTM   
Citations

3
checked on Mar 27, 2023

WEB OF SCIENCETM
Citations

5
checked on Mar 12, 2023

Page view(s)

45
checked on Mar 24, 2023

Google ScholarTM

Check

Altmetric

Altmetric

Related Items in TAIR


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Sherpa Romeo網站查詢,以確認出版單位之版權政策。
    Please use Sherpa Romeo to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)
Build with DSpace-CRIS - Extension maintained and optimized by Logo 4SCIENCE Feedback