https://scholars.lib.ntu.edu.tw/handle/123456789/514745
Title: | Effects of medication, treatment, and behavioral beliefs on intentions to take medication in patients with familial hypercholesterolemia | Authors: | Hagger M.S. Hardcastle S.J. Hu M. Kwok S. Lin J. Nawawi H.M. Pang J. Santos R.D. Soran H. TA-CHEN SU Tomlinson B. Watts G.F. |
Keywords: | Beliefs about medicines; Common sense model; Hyperlipidemia; Illness perceptions; Theory of planned behavior | Issue Date: | 2018 | Publisher: | Elsevier Ireland Ltd | Journal Volume: | 277 | Start page/Pages: | 493-501 | Source: | Atherosclerosis | Abstract: | Background and aims: Although familial hypercholesterolemia (FH) can be effectively managed using cholesterol-lowering medication, patients often fall short of complete treatment adherence. Identifying the psychological factors associated with self-regulation of FH medication is important to inform interventions to maximize adherence. The aim of the present study was to test an integrated psychological model in predicting FH patients’ intentions to take medication. Methods: FH patients attending clinics in seven countries were invited to participate in a cross-sectional survey study. Consenting patients (N = 551) completed self-report measures of generalized beliefs about medication overuse and harms, beliefs in treatment effectiveness, specific beliefs about taking medication (attitudes, subjective norms, perceived behavioral control), and intentions to take medication. Participants also completed measures of demographic variables (age, gender, education level, income, cardiovascular disease status). Data were analysed using path analysis controlling for country and demographic variables. Results: Attitudes (β =.331, p<0.001), subjective norms (β =.121, p=0.009), and beliefs about medication overuse (β = ?.160, p<0.001) were significant predictors of intentions to take medication. Treatment beliefs predicted intentions indirectly (β =.088, p<0.001) through attitudes and subjective norms. There was also an indirect effect of beliefs about medication overuse on intentions (β = ?.045, p=0.056), but the effect was small compared with the direct effect. Conclusions: The findings indicate the importance among FH patients of specific beliefs about taking medication and generalized beliefs about medication overuse and treatment in predicting medication intentions. When managing patients, clinicians should emphasize the efficacy of taking cholesterol-lowering drugs and the importance of treatment outcomes, and allay concerns about medication overuse. ? 2018 Elsevier B.V. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049319714&doi=10.1016%2fj.atherosclerosis.2018.06.010&partnerID=40&md5=1c6cc0960ac4b6152d18a9954e00a2ee https://scholars.lib.ntu.edu.tw/handle/123456789/514745 |
ISSN: | 0021-9150 | DOI: | 10.1016/j.atherosclerosis.2018.06.010 | SDG/Keyword: | hypocholesterolemic agent; biological marker; hypocholesterolemic agent; low density lipoprotein cholesterol; adult; Article; attitude to illness; drug efficacy; familial hypercholesterolemia; female; health belief; health literacy; human; major clinical study; male; medication compliance; medication overuse; middle aged; patient attitude; prescription; priority journal; self report; Theory of Planned Behavior; treatment outcome; aged; attitude to health; behavior; blood; clinical trial; cross-sectional study; down regulation; familial hypercholesterolemia; medication compliance; multicenter study; psychological model; psychology; risk assessment; self care; Adult; Aged; Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Cross-Sectional Studies; Down-Regulation; Female; Health Knowledge, Attitudes, Practice; Humans; Hyperlipoproteinemia Type II; Intention; Male; Medication Adherence; Middle Aged; Models, Psychological; Risk Assessment; Self Care; Treatment Outcome |
Appears in Collections: | 醫學系 |
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