Association between type 2 diabetes and cancer incidence in Taiwan: data from a prospective community-based cohort study
Journal
Acta Diabetologica
Journal Volume
54
Journal Issue
5
Pages
455
Date Issued
2017-05
Author(s)
Wei-Sin Yang
Pei-Chun Chen
Hsiu-Ching Hsu
Yuan-Teh Lee
Abstract
Aims: Evidence of a role for type 2 diabetes in overall cancer risk and risk for specific types of cancer is limited in ethnic Chinese populations. We therefore investigated whether there is an association between diabetes and cancer incidence in Taiwan. Methods: This study recruited a total of 3602 adults aged 35?years or over (average 54.9?±?12.3?years, 52.8% women). Participants with fasting glucose ?126?mg/dL, or taking hypoglycemic medications, were classed as having type 2 diabetes. Cancer incidence was established through regular follow-up interviews and medical records. Cox proportional hazard regression models were used to examine associations for diabetes with risk of all-cause and site-specific cancers. Results: During a median of follow-up of 10.5?years, 275 individuals developed cancer, including 157 digestive cancers and 31 urinary cancers. Younger participants (aged?
SDGs
Other Subjects
antidiabetic agent; glucose; adult; Article; cancer incidence; cancer localization; cancer risk; Chinese; cohort analysis; community assessment; controlled study; digestive system cancer; disease association; ethnicity; female; follow up; groups by age; human; kidney cancer; major clinical study; male; medical record; middle aged; non insulin dependent diabetes mellitus; prospective study; Taiwan; aged; Asian continental ancestry group; demography; Diabetes Mellitus, Type 2; incidence; Neoplasms; risk factor; Adult; Aged; Asian Continental Ancestry Group; Cohort Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Neoplasms; Prospective Studies; Residence Characteristics; Risk Factors; Taiwan
Publisher
Springer-Verlag Italia s.r.l.
Type
journal article