https://scholars.lib.ntu.edu.tw/handle/123456789/514830
標題: | Effects of personal exposure to particulate matter and ozone on arterial stiffness and heart rate variability in healthy adults | 作者: | CHANG-FU WU Kuo I.-C. TA-CHEN SU Li Y.-R. LIAN-YU LIN CHANG-CHUAN CHAN Hsu S.-C. |
公開日期: | 2010 | 卷: | 171 | 期: | 12 | 起(迄)頁: | 1299-1309 | 來源出版物: | American Journal of Epidemiology | 摘要: | The effects on heart rate variability (HRV) and arterial stiffness from exposure to ambient particulate matter and ozone have not been studied simultaneously. The aim of this study was to analyze these effects with refined exposure estimates from personal measurements of ozone and size-resolved particulate matter mass concentrations. The authors recruited 17 mail carriers in a panel study in Taipei County, Taiwan, during February-March, 2007, and each subject was followed for 5-6 days. Personal ozone and size-fractionated particulate matter exposures were monitored during working hours while carriers delivered mail outdoors. Cardiovascular effects were evaluated with heart rate variability (HRV) indices and an arterial stiffness index, the cardio-ankle vascular index (CAVI). The authors used linear mixed models to examine the association between personal exposure data and the HRV index and CAVI. They found that an interquartile range increase in personal exposure to ozone and particulate matter of between 1.0 and 2.5 μm was associated with a 4.8% and 2.5% increase in CAVI, respectively, in the single-pollutant models. In contrast, the personal exposure data showed no significant effects on HRV. In 2-pollutant models, personal ozone exposure remained significantly associated with the CAVI measurements. The study results indicate that vascular function may be more sensitive to air pollutants than the autonomic balance. ? 2010 The Author. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953198025&doi=10.1093%2faje%2fkwq060&partnerID=40&md5=bbcd7064ea2e15ef5346fee9cee907d3 https://scholars.lib.ntu.edu.tw/handle/123456789/514830 |
ISSN: | 0002-9262 | DOI: | 10.1093/aje/kwq060 | SDG/關鍵字: | ozone; adult; air quality; atmospheric pollution; cardiovascular disease; health status; linearity; occupational exposure; ozone; panel data; particle size; particulate matter; adult; air pollutant; arterial stiffness; article; cardiovascular effect; clinical evaluation; environmental exposure; follow up; heart rate variability; human; male; monitoring; normal human; outcome assessment; panel study; particulate matter; sampler; semiconductor; sensor; Taiwan; Adult; Air Pollutants; Arteries; Dose-Response Relationship, Drug; Electrocardiography; Environmental Exposure; Female; Heart Rate; Humans; Male; Middle Aged; Models, Statistical; Ozone; Particulate Matter; Taiwan; Taipei; Taiwan |
顯示於: | 醫學系 |
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