Left ventricular mass and correlated atherosclerotic risk factors in young adolescents: Report from Chin-Shan community cardiovascular study in TWN
Journal
Atherosclerosis
Journal Volume
155
Journal Issue
2
Pages
431-437
Date Issued
2001
Author(s)
Abstract
Various subclinical disease indicators can be used as an early stage marker of atherosclerosis. Left ventricular (LV) mass has been related to cardiovascular morbidity and mortality. The distribution of LV mass in Chinese is rarely studied and nothing is known about its relationships with various atherosclerotic risk factors in young teenagers, in particular, aspects of lipid profiles. We performed a community-based survey of 523 males and 555 females, aged 12-15, in Chin-Shan, a suburb area near Taipei, Taiwan. LV mass was calculated from the Penn convention. Normalized LV mass by height with power of 2.7 was defined. LV mass and normalized LV mass were significantly greater in males than in females. There were significant positive correlation coefficients between LV mass and age, blood pressure, body mass index, low density lipoprotein cholesterol (LDL-C), apolipoprotein (Apo) B, fasting insulin levels and significant negative correlation coefficients between LV mass and high density lipoprotein cholesterol (HDL-C) and Apo A1 level in both genders. Multiple linear regression models showed gender and body mass index (BMI) were important factors associated with LV mass or normalized values for adolescents. Age and systolic blood pressure were also significant predictors of LV mass, but not of normalized LV mass values. LV mass values were found to be negatively associated with HDL-C values at marginal statistically significant level. Age and BMI are the most significant factors of echocardiographic LV mass distributions in young adolescent in Taiwan. LV mass may also be associated with atherosclerotic risk factors. ? 2001 Elsevier Science Ireland Ltd.
SDGs
Other Subjects
apolipoprotein A1; apolipoprotein B; high density lipoprotein cholesterol; insulin; low density lipoprotein cholesterol; adolescent; age; article; atherosclerosis; blood sampling; body mass; cardiovascular risk; controlled study; correlation function; echocardiography; female; gender; heart left ventricle mass; human; insulin blood level; major clinical study; male; morbidity; mortality; prediction; priority journal; school child; statistical analysis; systolic blood pressure; Taiwan; Adolescent; Apolipoproteins B; Arteriosclerosis; Blood Pressure; Body Constitution; Body Mass Index; Child; Cholesterol, LDL; Cross-Sectional Studies; Female; Heart Ventricles; Humans; Hypertrophy, Left Ventricular; Insulin; Lipids; Male; Organ Size; Risk Factors; Suburban Population; Taiwan
Type
journal article