High risk of herpes zoster among patients with advance acute kidney injury - A population-based study
Journal
Scientific Reports
Journal Volume
5
Pages
13747
Date Issued
2015
Author(s)
Abstract
The risk for herpes zoster (HZ) in acute kidney injury (AKI) survivors was never explored. We identified 2,387 adults in the Taiwan National Health Insurance Research Database who recovered from dialysis-requiring AKI and matched them with non-recovery and non-AKI patients by propensity score. During a mean follow-up of 2.7 years, the incidences of HZ were 6.9, 8.2 and 4.8 episodes per 1,000 person-years in AKI-non-recovery, AKI-recovery and non-AKI group, respectively. The recovery group was more likely to develop herpes zoster than those without acute kidney injury [incidence-rate ratios 1.71, 95% confidence interval 1.16-2.52; p=0.007]. Patients without acute kidney injury were less likely to develop herpes zoster than those AKI, recovered from dialysis or not (hazard ratio HR 0.66, 95% CI 0.46-0.95). Dialysis-requiring acute kidney injury poses a long-term risk of herpes zoster after hospital discharge. Even patients who have recovered from dialysis still carry a significantly higher risk of developing herpes zoster.
SDGs
Other Subjects
Acute Kidney Injury; age distribution; causality; comorbidity; disease free survival; female; hemodialysis; herpes zoster; hospitalization; human; male; middle aged; population dynamics; prevalence; risk assessment; sex ratio; statistics and numerical data; survivor; Taiwan; Acute Kidney Injury; Age Distribution; Causality; Comorbidity; Disease-Free Survival; Female; Herpes Zoster; Hospitalization; Humans; Male; Middle Aged; Population Dynamics; Prevalence; Renal Dialysis; Risk Assessment; Sex Distribution; Survivors; Taiwan
Publisher
Nature Publishing Group
Type
journal article