https://scholars.lib.ntu.edu.tw/handle/123456789/515117
標題: | Impact of body mass on outcomes of geriatric postoperative acute kidney injury patients | 作者: | CHIA-TER CHAO VIN-CENT WU Tsai H.-B. Wu C.-H. YU-FENG LIN KWAN-DUN WU Ko W.-J. |
公開日期: | 2013 | 出版社: | Lippincott Williams and Wilkins | 卷: | 41 | 期: | 5 | 起(迄)頁: | 400-405 | 來源出版物: | Shock | 摘要: | Background: Acute kidney injury (AKI) frequently occurs in hospitalized patients, particularly in the elderly. However, studies on outcome-modifying factors in geriatric patients with AKI are absent, especially the influence of body mass index (BMI). Methods: We performed a retrospective analysis of a prospectively collected multicenter observational cohort, which enrolled elderly (?65 years) who developed AKI after major surgery in the intensive care units. We analyzed in-hospital mortality within BMI category utilizing Cox proportional hazard regression analysis and generalized additive modeling. Results: Data of a total of 2,015 postoperative elderly patients were retrieved and analyzed. Generalized additive modeling showed that elderly AKI patients with a BMI between 21 and 31 kg/m2 (normal) had a lower mortality risk than those with a BMI of less than 21 kg/m2 (underweight) or 31 kg/m2 or greater (obese). Both underweight and obese individuals had a greater risk of mortality compared with patients with normal BMI. Conclusions: The U-shaped association of BMI with hospital mortality in geriatric AKI patients contains a widened base and a shifted nadir comparing with chronic dialysis and other AKI patients. This finding is interesting and warrants our attention. ? 2014 by the Shock Society. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84901459237&doi=10.1097%2fSHK.0000000000000143&partnerID=40&md5=965e9a72fc579e364dbf2b4bc023325e https://scholars.lib.ntu.edu.tw/handle/123456789/515117 |
ISSN: | 1073-2322 | DOI: | 10.1097/SHK.0000000000000143 | SDG/關鍵字: | acute kidney failure; aged; APACHE; body mass; Conference Paper; controlled study; female; follow up; geriatric patient; human; length of stay; major clinical study; male; multicenter study; obesity; observational study; pacemaker implantation; postoperative complication; prospective study; sensitivity analysis; treatment outcome; underweight; Acute Kidney Injury; mortality; pathology; proportional hazards model; retrospective study; very elderly; Acute Kidney Injury; Aged; Aged, 80 and over; Body Mass Index; Female; Humans; Male; Proportional Hazards Models; Retrospective Studies |
顯示於: | 醫學系 |
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