Functional MRI in the assessment of cortical activation during gait-related imaginary tasks
Journal
Journal of Neural Transmission
Journal Volume
116
Pages
1087 -1092
Date Issued
2009
Author(s)
J-J Wang
Y-Y Wai
Y-H Weng
K-K Ng
Y-Z Huang
L. Ying
H-L Liu
C-H Wang
J-J Wang
Y-Y Wai
Y-H Weng
K-K Ng
Y-Z Huang
L. Ying
H-L Liu
C-H Wang
Abstract
Imaginary tasks can be used to investigate the neurophysiology of gait. In this study, we explored the cortical control of gait-related imagery in 21 healthy volunteers using functional magnetic resonance imaging. Imaginary tasks included gait initiation, stepping over an obstacle, and gait termination. Subjects watched a video clip that showed an actor in gait motion under an event-related design. We detected activation in the supplementary motor area during major gait-related imagery tasks, and especially during gait initiation. During gait termination and stepping over an obstacle, the amount of cortical resources allocated to the imaginary tasks included a large visuomotor network comprising the dorsal and ventral premotor areas. We conclude that our paradigm to study the cortical control of gait may help in elucidating the pathophysiology of higher-level gait disorders.
Type
journal article