https://scholars.lib.ntu.edu.tw/handle/123456789/517377
標題: | Comparison of tissue architectural changes between radiofrequency ablation and cryospray ablation in barretts esophagus using endoscopic three-dimensional optical coherence tomography | 作者: | Tsai T.-H. Zhou C. HSIANG-CHIEH LEE Tao Y.K. Ahsen O.O. Figueiredo M. Adler D.C. Schmitt J.M. Huang Q. Fujimoto J.G. Mashimo H. Tsai T.-H. Zhou C. Tao Y.K. Ahsen O.O. Figueiredo M. Adler D.C. Schmitt J.M. Huang Q. Fujimoto J.G. Mashimo H. |
公開日期: | 2012 | 來源出版物: | Gastroenterology Research and Practice | 摘要: | Two main nonsurgical endoscopic approaches for ablating dysplastic and early cancer lesions in the esophagus have gained popularity, namely, radiofrequency ablation (RFA) and cryospray ablation (CSA). We report a uniquely suited endoscopic and near-microscopic imaging modality, three-dimensional (3D) optical coherence tomography (OCT), to assess and compare the esophagus immediately after RFA and CSA. The maximum depths of architectural changes were measured and compared between the two treatment groups. RFA was observed to induce 230∼260 m depth of architectural changes after each set of ablations over a particular region, while CSA was observed to induce edema-like spongiform changes to 640 m depth within the ablated field. The ability to obtain micron-scale depth-resolved images of tissue structural changes following different ablation therapies makes 3D-OCT an ideal tool to assess treatment efficacy. Such information could be potentially used to provide real-time feedback for treatment dosing and to identify regions that need further retreatment. Copyright © 2012 Tsung-Han Tsai et al. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84864925030&doi=10.1155%2f2012%2f684832&partnerID=40&md5=81d3ce1831440799cde9766cf4ca8804 https://scholars.lib.ntu.edu.tw/handle/123456789/517377 |
DOI: | 10.1155/2012/684832 | SDG/關鍵字: | article; Barrett esophagus; clinical article; comparative study; cryoablation; cryospray ablation; follow up; human; lower esophagus sphincter; optical coherence tomography; radiofrequency ablation; three dimensional imaging; tissue structure |
顯示於: | 電機工程學系 |
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