https://scholars.lib.ntu.edu.tw/handle/123456789/517730
Title: | Minimal residual disease in hypopigmented mycosis fungoides | Authors: | Hsiao P.-F. Hsiao C.-H. TSEN-FANG TSAI Jee S.-H. |
Issue Date: | 2006 | Journal Volume: | 54 | Journal Issue: | 5 SUPPL. 1 | Start page/Pages: | S198-S201 | Source: | Journal of the American Academy of Dermatology | Abstract: | We describe the case of a 13-year-old boy with stage I hypopigmented mycosis fungoides in whom minimal residual disease was detected with T-cell receptor γ-polymerase chain reaction after the disease was in complete clinical remission. We further cloned and sequenced the T-cell receptor γ-polymerase chain reaction product of the lesion in remission and found that the original T-cell clone still existed in decreased amounts. The patient was followed up for 3 1/2 years without any new lesions developing. The clinical significance of this residual malignant T-cell clone in mycosis fungoides remains to be elucidated. ? 2006 American Academy of Dermatology, Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646068057&doi=10.1016%2fj.jaad.2005.08.044&partnerID=40&md5=afb87ffae214c8f2e3119e15c147a124 https://scholars.lib.ntu.edu.tw/handle/123456789/517730 |
ISSN: | 0190-9622 | DOI: | 10.1016/j.jaad.2005.08.044 | SDG/Keyword: | carmustine; T lymphocyte receptor; adolescent; anamnesis; article; case report; DNA sequence; follow up; human; human tissue; hypopigmentation; laboratory test; lymphocyte clone; male; minimal residual disease; mycosis fungoides; polymerase chain reaction; priority journal; remission; Adolescent; Antineoplastic Agents, Alkylating; Carmustine; Humans; Male; Mycosis Fungoides; Neoplasm, Residual; Pigmentation Disorders; Polymerase Chain Reaction; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Skin Neoplasms; Skin Pigmentation |
Appears in Collections: | 醫學系 |
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