https://scholars.lib.ntu.edu.tw/handle/123456789/517801
標題: | Using optical coherence tomography to assess the role of age and region in corneal epithelium and palisades of vogt | 作者: | Lin H.-C. Tew T.B. YI-TING HSIEH Lin S.-Y. Chang H.-W. FUNG-RONG HU WEI-LI CHEN |
關鍵字: | Age; Anterior segment OCT; Limbus; Palisades of vogt | 公開日期: | 2016 | 卷: | 95 | 期: | 35 | 來源出版物: | Medicine (United States) | 摘要: | Using spectral-domain optical coherence tomography (OCT) to observe the morphology and epithelial thickness (ET) of the palisades of Vogt (POV), and to evaluate the role of age and region on these structures. One hundred twelve eyes of 112 healthy subjects were enrolled and divided into 4 groups: A (0-19), B (20-39), C (40-59), and D (?60 years old). RTvue-100 OCT was applied on the cornea and the limbus. The morphology of the subepithelial stroma underneath the epithelium of POV was classified into typical and atypical types. Maximum ET of POV was measured manually from OCT images. The positive rate of typical POV in superior, nasal, temporal, and inferior limbus was: Group A: 100%, 69.2%, 65.4%, 100%; Group B: 100%, 73.5%, 61.8%, 94.1%; Group C: 95.8%, 41.7%, 37.5%, 83.3%; Group D: 67.9%, 0%, 3.6%, 25%, showing a significant decreasing tendency with age. The maximum ET of POV in superior, nasal, temporal, and inferior limbus was: Group A: 103.5±10.1 um, 89.2±9.7 um, 87.9±13.6 um, 104.7±14.1 um; Group B: 111.4±15.8 um, 85.3±9.9 um, 88.2±8.6 um, 112.6±19.7 um; Group C: 116.4±16.4 um, 82.8±11.6 um, 87.0±11.6 um, 120.0±25.6 um; Group D: 96.3±17.9 um, 73.8±15.9 um, 79.2±16.7 um, 87.4±18.5 um. Age-dependent change was observed. In general, the maximum ET of POV in superior/inferior quadrants was thicker than the other 2 quadrants. Spectral-domain OCT is a useful tool to observe the limbal microstructure and provide invaluable information. Aging and anatomic regions had significant effects on the microstructure of these areas. Copyright ? 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84987730738&doi=10.1097%2fMD.0000000000004234&partnerID=40&md5=6851209638bbdd1932b2dd44c0a705eb https://scholars.lib.ntu.edu.tw/handle/123456789/517801 |
ISSN: | 0025-7974 | DOI: | 10.1097/MD.0000000000004234 | SDG/關鍵字: | adolescent; adult; aged; aging; Article; conjunctiva epithelium; cornea epithelium; cornea limbus; cornea stroma; cornea thickness; epithelial thickness; female; groups by age; human; male; normal human; optical coherence tomography device; palisades of vogt; priority journal; prospective study; spectral domain optical coherence tomography; visual system parameters; age; aging; anatomy and histology; child; cornea epithelium; diagnostic imaging; middle aged; optical coherence tomography; very elderly; young adult; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Child; Epithelium, Corneal; Female; Humans; Limbus Corneae; Male; Middle Aged; Tomography, Optical Coherence; Young Adult |
顯示於: | 醫學系 |
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